If you have been trying to get pregnant for a year or more without success, it’s time to search for an expert’s advice. […]
According to the World Health Organization (WHO), nowadays between 10 and 15% of couples have fertility issues and between 30 and 35% of the reasons for infertility can be found in the male partner. Therefore, improving semen quality is one of the main concerns amongst couples with reproduction issues. […]
Haemophilia is a genetic and congenital disorder that affects coagulation. Blood does not coagulate properly and, as a result, people with haemophilia have haemorrhage or bleeding episodes of varying severity and in different areas that can arise spontaneously or following trauma.
There are three types of hereditary haemophilia: […]
Owing to sociocultural and economic factors, there has been a considerable increase in recent years in the number of men over the age of 35 who wish to have children. As a couple ages, the probability that they will experience reproductive problems increases. The negative effect of maternal age on fertility has been widely documented and we know that fertility diminishes drastically after the age of 39. Maternal aging is also associated with miscarriage, pregnancy complications, congenital anomalies and an increase in perinatal mortality.
However, few studies analyse the effect of paternal age on success after the application of assisted reproduction technology (ART) and the results they provide are contradictory. It is true that the male reproductive function is less vulnerable than the female where the aging process is concerned, as is demonstrated by the fact that many babies have been born spontaneously to fathers who are in their seventies or eighties. However, some associations have been found in specific studies that relate a negative effect of advanced paternal age with: […]
Before seeking pregnancy, women generally plan their gestation and take nutritional supplements, such as folic acid, which is fundamental for the prevention of defects of the neural tube in the foetus.
For greater assurance that this stage will be happy and free from complications, it is important to undergo prior reproductive counselling. Furthermore, it is appropriate to consider the need for some kind of specific additional counselling, according to the characteristics of the case. […]
From the very moment when sperm fertilises an ova, a new embryo starts developing and a large number of cell divisions take place. This embryo development is observed in an in vitro fertilisation laboratory up until the blastocyst stage (day 5 or 6 of development). Sometimes during the cell division process, fragments of the embryo become isolated between cells that have developed correctly. These fragments come from embryo cell remains and can stop the embryo from developing correctly. One of the negative impacts consists of issues reaching the blastocyst stage and the posterior impact on implantation in the uterus. In fact, embryo fragmentation is one of the most significant characteristics used to determine embryo quality. […]
The question of relationships between blood relatives has been approached in many different ways throughout the course of history. There have been times when relationships of this kind have been commonly accepted, whilst at other times they have been prohibited for moral, religious or even scientific reasons.
Relationships between blood relatives were actively encouraged in some primitive cultures in order to promote clan unity. For example, marriage between members of the same family in ancient Egypt. The legislation in a large number of US States currently prohibits and actively pursues relationships between first cousins. […]
Are sterility and infertility the same?
No, they are two completely different concepts.
Sterility is the inability to conceive whilst infertility is the inability to complete a full term pregnancy and give birth to a healthy child. […]
Pre-implantation genetic diagnosis (PGD) is a technique that provides a ‘genetic understanding’ of the embryo before it is transferred to the uterus. Thanks to this technique, we are able to study the embryo’s chromosomal make-up and determine if it is a carrier of a hereditary condition of any kind. This information helps us to select the embryos that will lead to the birth of a healthy child. But how do we obtain this information?
Work is currently being carried out to discover non-invasive means of gathering genetic information from the embryo but, to date, the only means is an embryo biopsy. What is an embryo biopsy? […]
Genetics guidance is the exchange through which an expert in genetics provides patients and their families with information and support on a genetic condition, inheriting that condition, the risk of recurrence and the implications for the individual and his or her family.
The aim of genetics guidance is to support the decision-making process whilst taking the patient’s values and beliefs into account, and to proceed based on the decision taken.
In the specific case of reproduction guidance, it is a question of guiding couples who are in a reproductive stage of their lives and who wish to have children and/or who are currently expecting a child. Therefore, we generally have two types of patients who need reproduction guidance. Whilst there are fundamental differences between the two, the aims of the guidance process remain the same and include: […]