Progress in treatment for patients with poor ovarian response

Personalising courses of treatment is undoubtedly currently the
most important area of change in the field of medicine. A specific strategy should be designed
depending on each patient’s individual characteristics.

One of the key areas for developing personalised medical healthcare is the use of pharmacogenetics. A patient needs different doses or types of pharmaceutical drugs depending on certain genetic variations. […]

2019-01-23T10:37:32+02:0025 de January de 2019|0 Comments

AIDS. Assisted reproduction is the best option

The risk of contracting HIV during unprotected sexual intercourse is estimated to be between 0.5 and 1%. For serodiscordant couples (one partner is a carrier), trying for a child naturally can entail an elevated risk of transmission. In cases such as these, assisted reproduction techniques are an excellent choice for getting pregnant without the risk […]

2019-01-11T10:57:28+02:0011 de January de 2019|0 Comments

Embryo fragmentation

Embryo fragmentation is a phenomenon that takes place in most embryos and its origin is not entirely clear. Some studies would seem to suggest that the fragments come from cell remains that have no nucleus or that they are the result of the decomposition of one or more cells from the embryo itself. The oocyte plays the most important role in fragmentation. Poor oocyte quality can lead to embryos that are highly fragmented. Embryo quality is determined by several characteristics such as the number of cells, their size or if the cell interior has an abnormality of any kind such as granularity or vacuolisation. However, one of the factors that has most impact on embryo quality is the extent of fragmentation. Based on the amount, in percentage, of space that it occupies, fragmentation is categorised into 4 types or degrees. […]

2019-06-20T08:31:38+02:0021 de December de 2018|0 Comments

The importance of embryo nutrition in achieving a successful cycle of in vitro fertilisation (IVF): metabolomics

One of the main limitations of assisted reproduction techniques are its embryo implantation failure rates. The implantation rate is the embryo’s ability to implant in the mother’s uterus. In other words, not all embryos are able to give rise to a pregnancy. Some have a greater chance of doing so than others. If it were possible to select embryos with the greatest ability to implant, it would be possible to improve assisted reproduction technique success rates. […]

2018-12-14T10:23:05+02:0014 de December de 2018|0 Comments

Is there hope for me following fertilisation failure after ICSI?

In vitro fertilisation treatment (IVF) techniques consist of fertilising oocytes with spermatozoa in a laboratory. They are held under conditions that are similar to their natural environment and, a few days later, the best embryo is selected and placed in the woman’s uterus where it remains until it implants. From this point on, monitoring procedures are the same as in any other spontaneous or natural pregnancy. […]

2018-11-02T14:19:35+02:002 de November de 2018|0 Comments

Seminal lavage: what is it and what is it used for?

Human immunodeficiency virus (HIV), hepatitis C (HCV) and hepatitis B (HBV) are viruses that are transmitted through blood and body fluids as well as through vertical transmission (from the mother to the foetus).  As a result, couples wishing to get pregnant in which one partner is a carrier of a virus are faced with the question of whether or not it is possible to do so without the other partner getting infected. If the male partner has one of these viruses and his female partner does not (serodiscordant couples), assisted reproduction technology (ART) can be used in order to avoid transmission. […]

2018-10-03T09:50:57+02:005 de October de 2018|0 Comments

What is a hysterosalpingography?

A hysterosalpingography is an examination using x-rays and, as its name suggests, it is used for exploring the uterus (hystero-) and fallopian tubes (salpingo-).
The examination is rather uncomfortable but this is remedied by giving the patient some form of pain relief or muscle relaxant before proceeding. An alternative test called a hysterosonography does now exist, too. It is pain free, does not require the use of x-rays and, furthermore, obtains the same results as a hysterosalpingography. Nowadays, hysterosonographies are the preferred choice over hysterosalpingographies. This technique can be performed at Instituto Bernabeu and the results are provided immediately. […]

2018-09-28T09:08:28+02:0028 de September de 2018|0 Comments

What are the causes of recurrent pregnancy loss?

Spontaneous abortion is defined as an unexpected pregnancy loss before the foetus is viable. In other words, before week 22 of pregnancy and under 500g in weight. The frequency rate of spontaneous abortion is estimated to be between 15 and 20% amongst the general population and it is the most common of all complications during pregnancy.
A small percentage (between 2 and 5%) of cases are recurrent and this is what is known as recurrent pregnancy loss (RPL). […]

2018-09-11T17:49:04+02:0014 de September de 2018|0 Comments

The advantages of comprehensive chromosome screening (PGS/PGT-A/CCS) in women of an advanced maternal age

Women currently seek guidance on reproduction at a much older age than they did some years ago. As a result, amongst the women who undergo fertility treatment, there is a significant group of women of an advanced age and their prognosis is poorer. This is a huge challenge for reproduction specialists. […]

2018-09-06T09:36:01+02:007 de September de 2018|0 Comments

Polycystic Ovary Syndrome

The term polycystic ovary syndrome is used to define an ultrasound diagnosis characterised by the presence of 12 or more follicles in each ovary (between 2 and 9 mm in diameter) and/or an incremented ovary volume (>10 ml). Findings such as these in ultrasounds in a single ovary are sufficient in order to be able to give a diagnosis. However, since taking oral contraceptives can change ovary morphology, this diagnostic criteria does not apply to women who take oral contraceptives.
From a practical point of view, when assisted reproduction technology (ART) is being used, detection of polycystic ovaries in isolation is useful for predicting the ovary’s response to stimulation using drugs and the risk of ovarian hyperstimulation syndrome. […]

2019-12-04T13:23:49+02:0031 de August de 2018|1 Comment
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