The extent of the issue
Obesity is a public health issue both in the general population and in women of childbearing age. The figures are a proof of this and, far from improving, the problem has been getting progressively worse over the last few years.
Maternal obesity in the United States of America was calculated to be 7% in 1980 and had risen up to 24% by 1999. If we take into account both obesity and excess weight, the available data indicates that the figures were 37.1% in 1999 and 40.5% in 2003.
The NHANES (National Health and Nutrition Examination Survey) reveals obesity figures (BMI or body mass index ≥ 30 kg/m2) in women of reproductive age (20 to 39 years of age) of 31.9%.
In other words, one in every three women of a fertile age is obese. […]
The extent of the issue
Breast cancer is the most common malignant tumour found in women and it is the main cause of death in women due to cancer in the world.
Over the last few years, there has been an increase in this pathology in younger women and, at the same time, treatment has taken breast cancer survival rates to almost 85%. These facts and a pronounced trend towards delaying motherhood has generated a group of women whose ability to reproduce has been negatively affected before they have had the chance to turn their dream of becoming a mother into a reality. […]
The advantages of comprehensive chromosome screening (PGS/PGT-A/CCS) in women of an advanced maternal age
Women currently seek guidance on reproduction at a much older age than they did some years ago. As a result, amongst the women who undergo fertility treatment, there is a significant group of women of an advanced age and their prognosis is poorer. This is a huge challenge for reproduction specialists. […]
Hormones are messengers that are present in all multicellular organisms – be they animal or plant organisms – that coordinate the functions of each part of that organism.
The sex hormones par excellence are oestradiol in females and testosterone in males. However, the adrenal glands in men and women produce both hormones and they are both necessary for normal development of the two sexes. […]
A patient can be classified as having poor response when the number of oocytes obtained during a cycle of in vitro fertilisation is under what was expected. The criteria generally used to label a patient as a poor responder is when 3 or fewer oocytes are retrieved and she has incredibly low ovarian reserve markers (fundamentally, AMH and AFC). […]
Oocyte quality is one of the most important of the factors that have an impact on fertility in women. Optimum oocyte quality generally gives rise to embryos with an increased ability to implant in the uterus. […]
In the ovary, there are structures known as follicles that contain the oocytes or ova. When a patient undergoes in vitro fertilisation (IVF) treatment, ovarian reserve is one of the most relevant pieces of data and it is evaluated by means of an antral follicle count (follicles that are capable of responding to hormones during stimulation cycle). This information is essential in predicting the number of oocytes we will obtain following ovarian stimulation. Following an ultrasound scan and hormone level checks, the gynaecologist decides when ovulation should be triggered in the patient. […]
Fragile X syndrome is one of the most common causes of hereditary intellectual disability.
The gene responsible for the disease is known as FMR1 and it is found in the X sex chromosome. As a result, both the transmission and the severity of the disorder varies in each sex. As a general rule, men are said to suffer from it whilst women are said to transmit it.
There is a repeat region in the FMR1 gene (expansion) and its size determines whether or not the individual has the disorder or not, as indicated below. […]
If you have been trying to get pregnant for a year or more without success, it’s time to search for an expert’s advice. […]
Hepatitis is severe or chronic inflammation of the liver.
There are several possible causes including infections (viral, bacterial or parasitic).
The most common cause is a viral infection and, within these, hepatitis B (HBV) and hepatitis C (HCV) viruses are of particular relevance. It is possible to get infected as a result of contact in blood and contaminated objects (unsterilised surgical material, syringes or needles), due to sexual transmission through mucous membranes and so-called vertical transmission (transmission from mother to child, particularly during childbirth). The chances of this type of transmission are the same in both vaginal and caesarean births. […]