Poor Ovarian Response Unit

Choosing a fertilisation technique when oocyte counts are poor. IVF or ICSI?

A low ovarian response is an increasingly common situation for clinicians. It is mainly associated with delayed motherhood and, accordingly, with lower ovarian reserves. In this type of patients, the number of oocytes retrieved after puncture is normally limited. In this situation, choosing the most adequate fertilisation technique, conventional IVF or Intracytoplasmic Sperm Injection (ICSI), may stir a little controversy (of course, provided that the sperm quality and the medical history lead us to consider conventional IVF as a reasonable option).

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2020-07-02T12:37:19+02:007 de May de 2020|0 Comments

Genetics in premature ovarian failure and menopause

Oocytes are the female gametes, cells that, upon being fertilised by the sperm, will produce an embryo. In humans, the number of oocytes that females have throughout their lives is not unlimited; they are born instead with a limited number. These oocytes gradually run out in each menstruation until their supply becomes completely exhausted at menopause.

It is said that women suffer from premature ovarian failure when menstruation ceases because the oocyte supply has become exhausted at an earlier age than the age when the natural decline of ovarian function occurs (at 50, approximately). In cases where oocytes are still produced in women suffering from premature ovarian failure, they do not respond satisfactorily to the hormones responsible for their development and maturation.

Premature ovarian failure may have important consequences for women:

Obviously, in their fertility: These women cannot conceive naturally and require assisted reproduction techniques in order to bear offspring. These patients also have a high risk that their oocytes will not respond to the In Vitro Fertilisation cycle, thus putting the success of the treatment in danger.On the other hand, the absence of female hormones due to low ovarian activity has serious consequences for health, mainly in cases of cardiovascular disease and osteoporosis.

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2020-05-27T16:31:11+02:005 de May de 2020|0 Comments

A father’s age and its impact on the health of his children

Anyone who works in the field of fertility puts a great deal of time and effort into working out how to improve pregnancy rates. However, significantly less time is spent thinking about the period that follows gestation or the birth of a healthy child. It’s time to ask ourselves if helping to build healthy and happy families […]

2020-01-24T09:54:26+02:0024 de January de 2020|0 Comments

What can we see in ultrasound scans: follicles or oocytes?

Mistaking ovarian follicles for oocytes is one of the most common errors made by patients.

During ovarian stimulation, whether this is for regulating ovulation for insemination or for in vitro fertilisation, patients are administered different types of medicines depending on each case. However, there is one common aim: predicting and causing ovulation. This can be just once for patients attempting managed sexual intercourse and […]

2020-01-10T09:52:05+02:0010 de January de 2020|0 Comments

Anti-müllerian hormone (AMH) is no longer a crystal ball

Anti-müllerian hormone (AMH) is used in reproductive medicine as an ovarian reserve marker. This hormone is detected using a simple blood analysis and, in conjunction with a follicle count ultrasound scan on the ovaries, it helps us to predict a patient’s response to stimulation. This is mainly true when patients have a limited prognosis.

In any case, despite how […]

2019-07-01T09:02:31+02:005 de July de 2019|0 Comments

Why hasn’t my assisted reproduction treatment worked?

The miracle of conception involves an intimate union between the ova and spermatozoon, appropriate evolution of the fertilised embryo and, furthermore, an ideal environment inside the uterus so that implantation can take place. Whilst this process might seem simple, it is much more complex than we might think, particularly in human beings. Only 30% of our conceptions end in […]

2019-06-13T09:00:34+02:0014 de June de 2019|0 Comments

Poor ovarian reserve; which means of diagnosis is the most reliable?

If we take into account that women’s oocytes develop before they are even born and that, after birth, the oocytes progressively decrease in number until they run out completely when women reach the menopause, the concept of ovarian reserve refers to the oocytes that are in a woman’s ovaries at any given time.

Assessing ovarian reserve is particularly important if […]

2019-05-31T08:53:37+02:0031 de May de 2019|0 Comments

What tests do I need to have before egg donation treatment?

Egg donation has become an option for women who, for whatever reason, can no longer use their own ova. For example, due to poor ovarian reserve, poor oocyte quality and premature menopause.

The process is widely used in Spain. As well as exceeding organ
donations and transplants in number, we also have the largest number of egg
donors in Europe.

It […]

2019-02-15T09:45:38+02:0015 de February de 2019|0 Comments

Progress in treatment for patients with poor ovarian response

Personalising courses of treatment is undoubtedly currently the
most important area of change in the field of medicine. A specific strategy should be designed
depending on each patient’s individual characteristics.

One of the key areas for developing personalised medical healthcare is the use of pharmacogenetics. A patient needs different doses or types of pharmaceutical drugs depending on certain genetic variations. […]

2019-01-23T10:37:32+02:0025 de January de 2019|0 Comments

Obesity and fertility

The extent of the issue
Obesity is a public health issue both in the general population and in women of childbearing age. The figures are a proof of this and, far from improving, the problem has been getting progressively worse over the last few years.
Maternal obesity in the United States of America was calculated to be 7% in 1980 and had risen up to 24% by 1999. If we take into account both obesity and excess weight, the available data indicates that the figures were 37.1% in 1999 and 40.5% in 2003.
The NHANES (National Health and Nutrition Examination Survey) reveals obesity figures (BMI or body mass index ≥ 30 kg/m2) in women of reproductive age (20 to 39 years of age) of 31.9%.
In other words, one in every three women of a fertile age is obese. […]

2018-12-07T10:06:37+02:007 de December de 2018|0 Comments
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