Forum/Blog

The latest advances and professional information, proven and reliable on fertility and assisted reproduction, gynaecology, genetics, embryology, endocrinology and urology, written by the medical professionals of Instituto Bernabeu.

The importance of embryo nutrition in achieving a successful cycle of in vitro fertilisation (IVF): metabolomics

One of the main limitations of assisted reproduction techniques are its embryo implantation failure rates. The implantation rate is the embryo’s ability to implant in the mother’s uterus. In other words, not all embryos are able to give rise to a pregnancy. Some have a greater chance of doing so than others. If it were possible to select embryos with the greatest ability to implant, it would be possible to improve assisted reproduction technique success rates. […]

2018-12-14T10:23:05+00:0014 de December de 2018|0 Comments

Obesity and fertility

The extent of the issue
Obesity is a public health issue both in the general population and in women of childbearing age. The figures are a proof of this and, far from improving, the problem has been getting progressively worse over the last few years.
Maternal obesity in the United States of America was calculated to be 7% in 1980 and had risen up to 24% by 1999. If we take into account both obesity and excess weight, the available data indicates that the figures were 37.1% in 1999 and 40.5% in 2003.
The NHANES (National Health and Nutrition Examination Survey) reveals obesity figures (BMI or body mass index ≥ 30 kg/m2) in women of reproductive age (20 to 39 years of age) of 31.9%.
In other words, one in every three women of a fertile age is obese. […]

2018-12-07T10:06:37+00:007 de December de 2018|0 Comments

DNA fragmentation in sperm: TUNEL

When a couple fails to get pregnant or has an unsuccessful pregnancy, a number of tests performed on both partners is recommended. One of the basic tests in analysis of the male partner involves performing a seminogram or spermiogram that provides us with an initial indication of semen quality. This information can be supplemented with a sperm DNA fragmentation analysis, should this be considered necessary.
The DNA fragmentation test is a technique that supplements a study of the male factor in certain cases. […]

2018-11-28T09:56:53+00:0030 de November de 2018|0 Comments

Infertility in men and cryptorchidism

Cryptorchidism, from the Greek words kriptos (hidden) and orquis (testicle), is the failure of one or both testes to descend to the scrotum. It is estimated that between 2 and 5% of newborn boys have this abnormality although the figure rises to 30% when premature boys are taken into account. In many cases, the issue resolves itself naturally and, as a result, at one year of age, only 1% of boys have the condition. […]

2018-11-21T10:23:53+00:0023 de November de 2018|0 Comments

The impact of Turner syndrome on women

Turner syndrome is a chromosomal condition caused by partial or total loss of one of the X chromosomes.
All human beings have 23 pairs of chromosomes and this is what is known as the karyotype. It is where all genetic information is stored. In other words, it is what determines our external appearance, our personal physical characteristics, how our organs work, whether or not we will have certain illnesses and so on. There are 22 pairs of numerical chromosomes ranging from 1 to 22 and one pair of sex chromosomes: X and Y. Women have two X chromosomes – one from their father and one from their mother. Men have one X chromosome – from their mother – and one Y chromosome – from their father. If, when a female embryo is generated, incorrect division leading to total or partial loss of the X chromosome takes place, this generates an abnormal karyotype that is characteristic of women with Turner syndrome. The syndrome, by definition, does not occur in males because they only have one X chromosome and cannot live unless this chromosome is present. […]

2018-11-14T11:19:07+00:0016 de November de 2018|0 Comments

What is the impact of obesity on male fertility?

Obesity, when understood as a body mass index (BMI) in excess of 30kg/m2, is associated with numerous health issues including hypertension, diabetes, hypercholesterolemia and so on. It also affects fertility. In women, the impact of obesity is very clear. It generates hormonal abnormalities that have a direct impact on a woman’s ability to reproduce. As a result, obesity in women has been the subject of numerous studies and there are a large number of publications on the matter. […]

2018-11-09T13:11:18+00:009 de November de 2018|0 Comments

Is there hope for me following fertilisation failure after ICSI?

In vitro fertilisation treatment (IVF) techniques consist of fertilising oocytes with spermatozoa in a laboratory. They are held under conditions that are similar to their natural environment and, a few days later, the best embryo is selected and placed in the woman’s uterus where it remains until it implants. From this point on, monitoring procedures are the same as in any other spontaneous or natural pregnancy. […]

2018-11-02T14:19:35+00:002 de November de 2018|0 Comments

Can I take my frozen embryos, oocytes or spermatozoa with me?

In in vitro fertilisation (IVF) laboratories, embryo cryopreservation (freezing) the viable embryos that remain following embryo transfer or when transfer is postponed is common practice. Cryopreservation of sperm samples has also been common practice for years and oocyte freezing has joined this list more recently. […]

2018-10-24T09:12:06+00:0026 de October de 2018|0 Comments

Breast cancer and fertility

Breast cancer is the most common malignant tumour found in women and it is the main cause of death in women due to cancer in the world.
Over the last few years, there has been an increase in this pathology in younger women and, at the same time, treatment has taken breast cancer survival rates to almost 85%. These facts and a pronounced trend towards delaying motherhood has generated a group of women whose ability to reproduce has been negatively affected before they have had the chance to turn their dream of becoming a mother into a reality. […]

2018-10-17T09:07:54+00:0019 de October de 2018|0 Comments

The impact of cannabis on semen

Today’s post aims to explain the conclusions drawn from research performed by the Biology Department at Instituto Bernabeu in Alicante in collaboration with the Biotechnology Department at the University of Alicante. The work in question was awarded the ICIRA prize for research. The study looked into the effects of cannabinoids (marijuana derivatives) and substances that are produced by our organisms (endocannabinoids) on male fertility. […]

2018-10-08T17:23:32+00:0011 de October de 2018|0 Comments
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