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The latest advances and professional information, proven and reliable on fertility and assisted reproduction, gynaecology, genetics, embryology, endocrinology and urology, written by the medical professionals of Instituto Bernabeu.

Physiological conditions in embryo culture: reduction of the amount of oxygen in the incubator

Improving embryo culture by mimicking the conditions generated during in vivo culture is a key contributor towards improving success rates in couples who turn to in vitro fertilisation in order to solve their sterility issue.
In vitro culture of human embryos has traditionally been carried out in incubators in a controlled atmosphere at 6% CO2 and 21% O2. However, based on studies carried out on different species of mammals, we know that these conditions do not match those found in vivo in the fallopian tubes and the uterus where oxygen tension ranges between 2 and 8%. […]

2017-12-15T10:32:55+00:0015 de December de 2017|0 Comments

What became of my embryos? Haven’t I got embryos to freeze?

These are just some of the questions that couples might ask at an important time during their treatment, just before embryo transfer.
In all cases of fertility treatment involving the in vitro fertilisation (IVF) laboratory, it is essential that all couples are given extensive, detailed and personalised information. This means talking about the embryo fertilisation and development processes.
When only a few fertilised oocytes are available as a result of poor ovarian reserve, transfer is carried out on day 2 or 3 of development in around 60% of cases because at this stage we can clearly select the embryos that are suitable for transfer. In around half of these cases it is not possible to cryopreserve embryos for future attempts. […]

2017-12-05T11:22:45+00:007 de December de 2017|0 Comments

A comparison of the phases in IVF and ICSI treatment

1.- Ovarian stimulation in the patient is carried out by administering doses of hormones that stimulate ovarian function with the aim of achieving sufficient oocytes. The doses of the aforementioned hormones are personalised to each patient depending on her ovarian reserve and based on the results of antimullerian hormone levels in a blood test and a follicle count for each ovary using a vaginal ultrasound scan. Controlling each patient’s ovarian response is done over a series of vaginal ultrasound scans (an average of 3) and, in some cases, by checking oestradiol (the hormone produced by the ovary) levels in blood. Once the checks indicate that the ovary is ready, oocyte retrieval is scheduled. This period of ovarian stimulation lasts between 8 and 10 days in most women and does not affect the patient’s daily routine. […]

2017-11-29T12:47:52+00:001 de December de 2017|0 Comments

Pre-implantation genetic diagnosis (PGD): comprehensive chromosome screening

Pre-implantacional genetic diagnosis (PGD) is a technique used to detect genetic or chromosomal abnormalities and it is performed on the embryo prior to transfer to the mother’s uterus.
Its use is recommended in couples where one of the partners is a carrier of a genetic or chromosomal abnormality that either means they are unable to get pregnant or increases the risk of pregnancy loss or abnormalities in their children. In some cases, it is the only means of having biologically healthy children and, in others, it is an alternative to prenatal diagnosis. […]

2017-11-24T16:04:03+00:0024 de November de 2017|0 Comments

Egg donor DNA storage bank

Thanks to the donor DNA storage bank at Instituto Bernabeu, patients who need to make use of donated gametes for their fertility treatment may, at any time, make a request (further to egg donor consent) for necessary genetics studies to be carried out with a view to preventing and adequately treating any conditions that may affect their children […]

2017-11-15T12:28:55+00:0017 de November de 2017|0 Comments

What you should (or should not) eat in order to give birth to a healthy child

We are what we eat. This classic of all classics is particularly important from the time when we try to get pregnant and for the 9 months that a pregnancy lasts because the quality of our diet and whether or not we include or exclude certain nutrients from our diet is key to ensuring that the organism develops correctly.
WHAT YOU SHOULD EAT:
Everything our child needs it gets from our blood and our blood is nourished by what we eat. This period of a woman’s life does not combine well with diets aimed at losing weight: you need to go back to eating the carbohydrates that give you energy. This includes both the brown cereals that will help you to combat constipation thanks to the fibre they contain and the white ones that will help you to absorb iron and calcium. […]

2017-11-10T10:41:18+00:0010 de November de 2017|0 Comments

Genetic Incompatibility between the couple, does this exist?

It is thought that about 20% of the reproductive problems are genetic or chromosomal. That is why the genetic testing is now an essential part of the fertility study carried out on couples who come to our centre for help to have children. […]

2017-11-02T10:19:58+00:003 de November de 2017|0 Comments

How do genetics and epigenetics affect the embryo?

What are genetics and epigenetics?
Genetics and epigenetics are two, closely-related branches of biology. The former is much more well known and consists of studying how hereditary characteristics are passed on from generation to generation. DNA is the molecule in which genetic information is stored in a 4-letter code:  A, C, G and T. The combination of letters is not a matter of chance. On the contrary, they combine in a precise manner because, in living things, the 4 letters make up the code for generating the instructions (genes) for synthesising all proteins.  This DNA is in the nucleus of the cells linked to the histones around which DNA wraps itself, as if it were a spool of thread. […]

2017-10-27T11:32:14+00:0027 de October de 2017|0 Comments

Can the immune system have an impact on implantation failure and recurrent pregnancy loss?

The immune system plays a very important role in the health of human beings, acting as a defence barrier against harmful organisms or substances.
Immunology is a very complex area when trying to get pregnant or as a pregnancy progresses and it involves an elevated number of cell types and molecules that need to work in a coordinated and balanced manner. […]

2017-10-11T09:25:32+00:0020 de October de 2017|0 Comments

If you’re thinking about becoming a mother using donated eggs, here are eight questions and answers for you

As is only to be expected, women have a number of doubts when they first take the important decision to become a mother using an egg donated by another women. The first reaction is one of shock when a woman finds out that she will need to rely on egg donation. Once they have had time to come to terms with the situation, many women take it on board naturally and accept the option that will allow them to give birth to their child. For others, however, the process takes longer and it needs to be thought through before it can be accepted or, in some cases, rejected.
Women go through what is known as genetic mourning during the process when they become aware of the fact that the baby will not have their genes. According to the experts at Instituto Bernabeu, accepting this situation from the outset is the best way forward if patients are to avoid turning the doubts and questions that come up along the way into a concern or even an obsession for the future mother. […]

2017-10-11T14:43:31+00:0013 de October de 2017|0 Comments
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