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The latest advances and professional information, proven and reliable on fertility and assisted reproduction, gynaecology, genetics, embryology, endocrinology and urology, written by the medical professionals of Instituto Bernabeu.

Haemophilia, fertility and pregnancy

Haemophilia is a genetic and congenital disorder that affects coagulation. Blood does not coagulate properly and, as a result, people with haemophilia have haemorrhage or bleeding episodes of varying severity and in different areas that can arise spontaneously or following trauma.
There are three types of hereditary haemophilia: […]

2018-04-17T09:04:45+00:0017 de April de 2018|0 Comments

Mumps and male infertility

Parotitis, more commonly known as “mumps”, is a contagious viral disease that affects one or both parotid glands (major salivary glands) situated behind the ascending rami of the mandible. It is caused by the mumps virus and typically affects children and teenagers, although it may also cause infections in sensitive adults. In general, the disease produces lifetime immunity, and it may be prevented by the administration of the combined MMR vaccine. Mumps may affect other glands in the body, the central nervous system and the testicles. The most frequent complications are meningitis and testicular inflammation which may lead to infertility. This inflammation of the testicle is also known as mumps orchitis. It is not very frequent, affecting 1 per million inhabitants per year among the general population. […]

2018-04-05T09:14:33+00:006 de April de 2018|0 Comments

The advantages and disadvantages of transferring embryos during a natural or artificial cycle

Embryo transfer to the uterus is the pinnacle of all courses of assisted reproduction treatment. It cannot be left to chance. The endometrium needs to be receptive and facilitate embryo embedding.
The endometrium can be prepared with the aid of drugs (oestrogens) to simulate natural uterine behaviour – a substituted or artificial cycle – or transfer can be carried out whenever biologically most appropriate following ovulation – transfer during a natural cycle. […]

2018-03-28T12:54:41+00:0029 de March de 2018|0 Comments

Effects of advanced paternal age on fertility

Owing to sociocultural and economic factors, there has been a considerable increase in recent years in the number of men over the age of 35 who wish to have children. As a couple ages, the probability that they will experience reproductive problems increases. The negative effect of maternal age on fertility has been widely documented and we know that fertility diminishes drastically after the age of 39. Maternal aging is also associated with miscarriage, pregnancy complications, congenital anomalies and an increase in perinatal mortality.
However, few studies analyse the effect of  paternal age on success after the application of assisted reproduction technology (ART) and the results they provide are contradictory. It is true that the male reproductive function is less vulnerable than the female where the aging process is concerned, as is demonstrated by the fact that many babies have been born spontaneously to fathers who are in their seventies or eighties. However, some associations have been found in specific studies that relate a negative effect of advanced paternal age with: […]

2018-03-23T10:03:08+00:0023 de March de 2018|0 Comments

Relevance of reproductive counselling

Before seeking pregnancy, women generally plan their gestation and take nutritional supplements, such as folic acid, which is fundamental for the prevention of defects of the neural tube in the foetus.
For greater assurance that this stage will be happy and free from complications, it is important to undergo prior reproductive counselling. Furthermore, it is appropriate to consider the need for some kind of specific additional counselling, according to the characteristics of the case. […]

2018-03-14T10:36:37+00:0016 de March de 2018|0 Comments

Embryo transfer on day 4 – why not?

In most laboratories, embryo transfer traditionally takes place on day 2 to 3 of culture, or during blastocyst stage, whilst embryo transfer on day 4 is an alternative that has not commonly been adopted into laboratory practice.
When compared with embryo transfer during early stages, blastocyst transfer is generally accepted as superior. This is mainly for reasons of improved synchronisation between the embryo and the endometrium and more objective embryo selection once the genome has been activated. It means that a smaller number of embryos can be transferred, thus avoiding the risk of a multiple pregnancy. […]

2018-03-08T12:52:29+00:009 de March de 2018|0 Comments

IMSI, does it improve the results?

IMSI, or Intracytoplasmic morphologically selected sperm injection, is a technique that became popular over a decade ago.  It uses a very high-power microscope to examine and select the sperm that will then be introduced in the egg with the aim of increasing the possibilities of a successful implantation and reducing the probabilities of miscarriage. […]

2018-03-02T10:25:06+00:002 de March de 2018|0 Comments

Fragment removal

From the very moment when sperm fertilises an ova, a new embryo starts developing and a large number of cell divisions take place. This embryo development is observed in an in vitro fertilisation laboratory up until the blastocyst stage (day 5 or 6 of development). Sometimes during the cell division process, fragments of the embryo become isolated between cells that have developed correctly. These fragments come from embryo cell remains and can stop the embryo from developing correctly. One of the negative impacts consists of issues reaching the blastocyst stage and the posterior impact on implantation in the uterus. In fact, embryo fragmentation is one of the most significant characteristics used to determine embryo quality. […]

2018-02-20T15:37:38+00:0023 de February de 2018|0 Comments

Children born to blood relatives

The question of relationships between blood relatives has been approached in many different ways throughout the course of history. There have been times when relationships of this kind have been commonly accepted, whilst at other times they have been prohibited for moral, religious or even scientific reasons.
Relationships between blood relatives were actively encouraged in some primitive cultures in order to promote clan unity. For example, marriage between members of the same family in ancient Egypt. The legislation in a large number of US States currently prohibits and actively pursues relationships between first cousins. […]

2018-02-16T14:03:20+00:0016 de February de 2018|0 Comments

Sterility and Infertility

Are sterility and infertility the same?
No, they are two completely different concepts.
Sterility is the inability to conceive whilst infertility is the inability to complete a full term pregnancy and give birth to a healthy child. […]

2018-02-08T13:46:19+00:009 de February de 2018|0 Comments
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