A study by Instituto Bernabeu reveals a high risk of aneuploidies in embryos without PGT-A

May, 2nd 2024

A study by Instituto Bernabeu reveals a high risk of aneuploidies in embryos without PGT-A

Dr Eva M. García will present the results of this study at the next edition of the SEF congress

Dr Eva M. García from Instituto Bernabeu will give an oral presentation at the Spanish Fertility Society (SEF in Spanish) congress where she will present the results of a study conducted by Instituto Bernabeu estimating the risk of miscarriages or live births with chromosomal alterations in patients who undergo in vitro fertilisation (IVF) cycles without performing chromosomal analysis (PGT-A) to the embryos transferred.

The study, which analysed 9,224 embryos, found that 55% of them had chromosomal abnormalities. Of these, 7.3% were viable alterations, meaning that they could lead to pregnancy and subsequent birth of a child with a chromosomal disease.

The results of the study highlight the importance of PGT-A in increasing pregnancy rates, as selecting chromosomally normal embryos reduces the risk of miscarriages and births of children with chromosomal abnormalities,” explains Dr Garcia. In addition, this procedure improves the psychological state of patients because it can help reduce the anxiety and stress associated with IVF treatments, as it offers patients the possibility of transferring embryos with a higher potential for success.

Another advantage, explains the doctor, is that treatment costs are reduced: “by avoiding unnecessary transfers of embryos with chromosomal abnormalities, PGT-A can help reduce the costs associated with IVF cycles“.

Instituto Bernabeu has been using the PGT-A technique for years and offers it as an option for all patients undergoing IVF treatment.

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