Publicaciones científicas

Instituto Bernabeu es un referente en la investigación de la fertilidad y reproducción asistida con numerosos trabajos aceptados en congresos y revistas nacionales e internacionales.

Clinical efficacy of recombinant versus highly purified follicle-stimulating hormone according to follicle-stimulating hormone receptor genotype

  • 17-05-2016

Pharmacogenet Genomics. 2016 Jun;26(6):288-93.  Belén Lledó, Patricia Dapena, Jose A. Ortiz, Ruth Morales, Joaquín Llacer and Rafael Bernabeu

Can reproductive medicine help to understand the aetiopathogenesis of pre-eclampsia?

  • 01-04-2016
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Reproductive Medicine and Clinical Embryology (MEDRE). Vol. 03, 1-3. 2016. F. Sellers, J. Llácer y R. Bernabeu. 

Metabolites involved in cellular communication among human cumulus-oocyte-complex and sperm during in vitro fertilization

  • 01-11-2015
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Reproductive Biology and Endocrinology. November 2015. M.J. Gómez, E.M. García, J. Guerrero, S. Medina, M. J. Izquierdo, A. Gil, J. Orduna, M. Saviron, J. Ten, R. Bernabeu, M. Avilés, L. González

Androgen receptor CAG repeat length is associated with ovarian reserve but not with ovarian response.

  • 01-10-2014
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RBMOnline. Vol. 29, 509-515. October 2014. B. Lledo, J. Llácer, A. Turienzo, J.A. Ortiz, J. Guerrero, R. Morales, J. Ten, R. Bernabeu.

Pharmaceutical options for triggering of final oocyte maturation in ART.

  • 01-07-2014
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BioMed Research International. vol. 2014, Article ID 580171, 7 pages, 2014. doi:10.1155/2014/580171. July 2014J. C. Castillo, P. Humaidan, and R. Bernabeu

Pharmacogenetics of ovarian response

  • 02-06-2014
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 Pharmacogenomics. 15 (6), pp 885-893. June 2014B. Lledó, J. A. Ortíz, J. Llácer, R. Bernabeu

A multicenter prospective study to assess the effect of early cleavage on embryo quality, implantation, andlive-birth rate

  • 01-04-2014
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Fertility and Sterility Vol. 104, Issue 4. Pages 981-987. April 2014Maria José de los Santos, Ph.D.,Gemma Arroyo, Ph.D.,Ana Busquet, Ph.D.,Gloria Calderon, Ph.D.,Jorge Cuadros, Ph.D.,Maria Victoria Hurtado de Mendoza, Ph.D.,Marta Moragas, Ph.D.,Raquel Herrer, Ph.D., Agueda Ortiz, Ph.D.,Carme Pons, M.Sc.,Jorge Ten, Ph.D.,Miguel Angel Vilches, Ph.D., and Maria Jose Figueroa, Ph.D., for the ASEBIR Interest Group in Embryology.

Study of structural damage after sperm immobilisation prior to intracytoplasmic sperm injection in teratozoospermic males.

  • 14-01-2014
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International Journal of Andrology. Volume 12 (1):10–15. January-March 2014. María José Gómez-Torresa, Eva María García, Jaime Guerrero, Jose Luis Girela, Jorge Tena, Rafael Bernabeub y Joaquín De Juan

First place prize for original work. 8th Edition of Angel Bayo Awards. ASESA (Spanish Andrology Society). June 2015.

Negative effect of P72 polymorphism on p53 gene in IVF outcome in patients with repeated implantation failure and pregnancy loss

  • 01-11-2013
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Journal of Assisted Reproduction and Genetics. November 2013.B. Lledó, A. Turienzo, J.A. Ortíz, R. Morales, J. Ten, J. Llácer, and R. Bernabeu.

Capacitation and acrosome reaction changes α-tubulin immunodistribution in human spermatozoa

  • 01-10-2013
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RBMOnline. October 2013. M.M. Francou, J. Ten, J. De Juan and R. Bernabeu.

Characterization of a balanced complex chromosomal rearrangement carrier ascertained through a fetus with dup15q26.3 and del5p15.33: case report

  • 01-08-2013
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Human Fertility. August 2013. B. Lledó, J. A. Ortiz, R. Morales, I. Manchón, F. Galán, A. Bernabeu and R. Bernabeu.

Effect of follicle-stimulating hormone receptor N680S polymorphism on the efficacy of follicle-stimulating hormone stimulation on donor ovarian response.

  • 01-03-2013
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 Pharmacogenetics and Genomics. March 2013. B. Lledo, J. Guerrero, A. Turienzo, J.A. Ortiz, R. Morales, J. Ten, J. Llacer and R. Bernabeu.

Uterine arteriovenous malformation

  • 01-02-2013
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British Medical Journal (BMJ) Case Rep 2013.doi: 10.1136/bcr-2012-008443. February 2013.F. Sellers, A. Palacios, B. Moliner, R. Bernabeu.

New Approach for Chemometric Analysis of Mass Spectrometry Data

  • 01-02-2013

Analytical Chemistry. Vol.85 (6).pp 3053-3058. February 2013. F.C. Marhuenda-Egea, R. D. Gonsálvez-Álvarez, B. Lledó-Bosch, J. Ten, R. Bernabeu.

Androgen receptor Polymorphisms are associated with poor ovarian response

  • 03-09-2012
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Fertility and Sterility Vol. 98, Issue 3, Supplement, Page S114. September 2012. ASRM AbstractsJ. Llácer, J.A. Ortiz, J. Guerrero, B. Lledó, J. Ten, R. Bernabeu.2nd place ASRM award for the best conference poster.

Sperm deoxyribonucleic acid fragmentation level, as measured by tunel test, is not related with the IVF outcome in good prognosis women.

  • 03-09-2012
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Fertility and Sterility Vol. 98, Issue 3, Supplement, Page S150. September 2012. ASRM Abstracts. B. Lledó, R. Morales, A. Rodríguez, J. Ten, R. Bernabeu.

High ovarian stimulation doesn't impair embryo quality. Clinical evidence using comparative model with shared egg donors

  • 03-09-2012
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Fertility and Sterility Vol. 98, Issue 3, Supplement, Pages S171-S172. September 2012. ASRM Abstracts. J. Llácer, B. Moliner, A. Rodríguez, J. Guerrero, J. Ten, R. Bernabeu.

Effect of polymorphism in the promoter estrogen receptor alpha on sperm count

  • 03-09-2012
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Fertility and Sterility Vol. 98, Issue 3, Supplement, Page S243. September 2012.ASRM Abstracts. B. Lledó, A. M. Fabregat, R. Morales, J. A. Ortiz, J. Llácer, R. Bernabeu.

Intermediate and normal sized CGG repeat on the FMR1 gene does not negatively affect donor ovarian response

  • 01-02-2012
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Human Reproduction Vol. 27, No. 2. pp 609-614. February 2012. B. Lledo, J. Guerrero, J.A. Ortiz, R. Morales, J. Ten, J. Llácer, J. Giménez, R. Bernabeu.

Correlations between Different Heavy Metals in Diverse Body Fluids: Studies of Human Semen Quality

  • 02-01-2012
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Advances in Urology. Vol. 2012, Art. ID 420893, 11 pages. 2012. L. Mínguez-Alarcón, J. Mendiola, M. Roca, J.J. López-Espín, J.J. Guillén, J.M. Moreno, S. Moreno-Grau, M.J. Martínez-García, N. Vergara-Juárez, B. Elvira-Rendueles, A. García-Sánchez, J. Ten, R. Bernabeu, A.M. Torres-Cantero.

Relationships between heavy metal concentrations in three different bodily fluids and male reproductive parameters: a pilot study

  • 03-01-2011
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Environmental Health. 10:6. 2011. J. Mendiola, J.M. Moreno, M. Roca, N. Vergara-Juárez, M.J. Martínez-García, A. García-Sánchez, B. Elvira-Rendueles, S. Moreno-Grau, J.J. López-Espín, J. Ten, A.M. Torres-Cantero, R. Bernabeu.

Improving human embryos selection in IVF: non-invasive metabolomic and chemometric approach

  • 03-01-2011
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Metabolomics (2011) 7:247-256. 2011. F. C. Marhuenda-Egea, R. Gonsálvez-Álvarez, E. Martínez-Sabater, B. Lledó, JTen, R. Bernabeu.

Analysis of Placental Vascularization by Means of 3D Power Doppler in Women Pregnant Following Oocyte Donation

  • 02-08-2010
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Reproductive Sciences. Vol. 17, No. 8, pp 754-759. August 2010F. Sellers López, D. Orozco-Beltrán, V. Gil-Guillen, J.M. Lozano, A. Palacios, R. Bernabeu.

The paternal effect of chromosome translocation carriers observed from meiotic segregation in embryos

  • 01-07-2010
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Human Reproduction. Vol. 25, No. 7, pp 1843-1848. July 2010B. Lledó, J.A. Ortiz, R. Morales, J. Ten, P.E. de la Fuente, C. García-Ochoa, R. Bernabeu

A crucial step in assisted reproduction technology: human embryo selection using metabolomic evaluation

  • 01-07-2010
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Fertility and Sterility. Vol. 94. No. 2. 772-774, July 2010.F.C. Marhuenda-Egea, E. Martínez-Sabater, R. Gonsálvez-Álvarez, B. Lledó, J. Ten, R. Bernabeu.

A low intake of antioxidant nutrients is associated with poor semen quality in patients attending fertility clinics

  • 01-03-2010
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Fertility and Sterility. Vol. 93, No. 4, March 1, 2010J. Mendiola, A. M. Torres-Cantero, J. Vioque, J. M. Moreno-Grau, J. Ten, M. Roca, S. Moreno-Grau, R. Bernabeu.

Food intake and its relationship with semen quality: a case-control study

  • 02-03-2009
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Fertility and sterility Vol. 91, Nº3, March 2009J. Mendiola, A.M. Torres-Cantero, J.M. Moreno-Grau, J. Ten, M. Roca, S. Moreno Grau, R. Bernabeu.

Exposure to environmental toxins in males seeking infertility treatment: a case-controlled study

  • 01-01-2008
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Reproductive BioMedicine Online. Vol. 16, No 6, 842-850. 2008.J. Mendiola, A.M. Torres-Cantero, J.M. Moreno-Grau, J. Ten, M. Roca, S. Moreno-Grau, R. Bernabeu.

Occupational and Lifestyle Exposures on Male Infertility: A Mini Review

  • 01-01-2008
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The Open Reproductive Science Journal. Vol. 1, 16-21. 2008J. Ten, J. Mendiola, A.M. Torres-Cantero, J.M. Moreno-Grau, S. Moreno-Grau, M. Roca, J. Romero and R. Bernabeu.

Preimplantation genetic diagnosis of X-linked retinoschisis

  • 01-01-2008
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Reproductive BioMedicine Online Vol. 16, No. 6, 886-892. 2008B. Lledó, J. Ten, D. Rodríguez-, J. Llácer, R. Bernabeu.

Preimplantation genetic diagnosis of X-linked adrenoleukodystrophy with gender determination using multiple displacement amplification

  • 01-11-2007
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Fertility and Sterility. Vol. 88, No. 5, 1327-1333. November 2007B. Lledo, R. Bernabeu, J. Ten, F.M. Galan, L. Cioffi.

Sperm immobilized before intracytoplasmic sperm injection undergo ultrastructural damage and acrosomal disruption

  • 03-09-2007
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Fertility and Sterility. Vol. 88, No.3, 702-704. September 2007M.J. Gomez-Torres, J. Ten, J.L. Girela, J. Romero, R. Bernabeu, J. De Juan.

Development of Assisted Reproduction. Past, Present and Future of Technologies

  • 01-01-2007
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Bioforum Europe. Vol. 11, 64-65. 2007B. Lledó, J. Llácer, J. Ten and R. Bernabeu.

Donor oocyte dysmorphisms and their influence on fertilization and embryo quality

  • 01-01-2007
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Reproductive BioMedicine Online. Vol. 14. No. 1, 40-48. January 2007.J. Ten, J. Mendiola, J. Vioque, J. de Juan, R. Bernabeu.

Preimplantation genetic diagnosis of Marfan syndrome using multiple displacement amplification

  • 02-10-2006
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Fertility and Sterility. Vol. 86, No. 4, 949-955. October 2006. B. Lledó, J. Ten, F.M. Galán, R. Bernabeu.

Indomethacin effect on implantation rates in oocyte recipients

  • 01-02-2006
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Human Reproduction. Vol. 21, No. 2. pp. 364-369. February 2006M. Roca, A. Torres, J. Ten, R. Bernabeu.

Analysis of factors influencing pregnancy rates in homologous intrauterine insemination

  • 03-05-2004
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Fertility and Sterility Vol. 81, No. 5, 1308-1313. May 2004G. Ibérico, J. Vioque, N. Ariza, J.M. Lozano, M. Roca, J. Llacer, R. Bernabeu.

Follicular fluid markers of oocyte developmental potential

  • 01-04-2002
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Human Reproduction. Vol. 17, No.4. pp 1017-1022. April 2002C. Mendoza, E. Ruiz-Requena, E. Ortega, N. Cremades, F. Martínez, E. Greco, J. Tesarik and R. Bernabeu.

Historical comment on the debate: embryo implantation is the rubicon for the GnRH antagonist, and answer

  • 01-10-2001
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Human Reproduction. Vol. 16, No. 10, p. 2247. October 2001R. Bernabeu.

Developmental potential of elongating and elongated spermatids obtained after in-vitro maturation of isolated round spermatids

  • 03-09-2001
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Human Reproduction. Vol. 16, No.9. pp. 1938-1944, September 2001N. Cremades, M. Sousa, A. Barros and R. Bernabeu.

In-vitro maturation of round spermatids using co-culture on Vero cells

  • 03-05-1999
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Human Reproduction. Vol. 14, No. 5. pp. 1287-1293. May 1999.N. Cremades, A. Barros, M. Sousa, R. Bernabeu.

Effects of Agonist dose on in-vitro fertilization

  • 01-10-1998
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Human Reproduction. Vol.13. No. 10. pp. 2973-2974. October 1998. C. Álvarez and R. Bernabeu.

Successful pregnancy after spermatid injection

  • 01-07-1998
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Human Reproduction Vol. 13, No.7. pp. 1898-1900. July 1998N. Cremades, K. Takahashi, M. Sousa, R. Bernabeu.

Influence of gonadotrophin-releasing hormone agonist total dose in the ovarian stimulation in the long down-regulation protocol for in-vitro-fertilization

  • 01-11-1997
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Human Reproduction. Vol 12. No 11. Pp. 2366-2369. November 1997C. Álvarez, N. Cremades, N. Blasco and R. Bernabeu.

Deletion of chromosome 13: 46, XY del (13) (q14->qter) after in vitro fertilization and tubal embryo transfer

  • 01-07-1996

Journal of Assisted Reproduction and Genetics, Vol. 13, No 6. July 1996M. Bonada, N. Cremades, F. Galán, R. Bernabeu.

Sex selection may be inadvertently performed in in-vitro fertilization-embryo transfer programmes

  • 01-11-1995
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Human Reproduction. Vol. 10, No 11. pp. 2992-2998. November 1995JJ. Tarín, A. Baviera, M. Bonada, A. Cano and RBernabeu. 

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