What does informativity testing involve? Does informativity have to be tested at every cycle?
It is a previous step to PGD. Once the genetic testing that enables us to find the abnormal gene causing the disease has been performed, an informativity test becomes necessary. It involves developing a strategy to identify the abnormality in the couple's embryos in the safest way possible. Often, both healthy and affected members from both families have to participate in informativity tests. Informativity does not vary from one cycle to another. Therefore, it is enough to test it once before the beginning of the cycle, not being necessary to do it again.