If none of my family members are affected (de novo), can I undergo PGD?

Yes, you can. In cases like this, sperm has to be tested prior to embryos in case the male is affected by/the carrier of the disease, or oocytes in case it is the female that is affected by/the carrier of the disease. These cases are more complex, but PGD can be safely performed by means of this technique.

 

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