sperm DNA fragmentation

DNA fragmentation in sperm: TUNEL

When a couple fails to get pregnant or has an unsuccessful pregnancy, a number of tests performed on both partners is recommended. One of the basic tests in analysis of the male partner involves performing a seminogram or spermiogram that provides us with an initial indication of semen quality. This information can be supplemented with a sperm DNA fragmentation analysis, should this be considered necessary.
The DNA fragmentation test is a technique that supplements a study of the male factor in certain cases. […]

2018-11-28T09:56:53+02:0030 de November de 2018|0 Comments

Tobacco and semen quality

According to the World Health Organization (WHO), nowadays between 10 and 15% of couples have fertility issues and between 30 and 35% of the reasons for infertility can be found in the male partner. Therefore, improving semen quality is one of the main concerns amongst couples with reproduction issues. […]

2018-05-03T17:24:58+02:004 de May de 2018|0 Comments

How can the best spermatozoon for fertilising an egg be selected?

Selection of the spermatozoon capable of fertilising an egg and generating a viable embryo is a subject that has been covered in a great number of studies aiming to provide this question with an answer.
Although assisted reproduction techniques have been used for dealing with fertility issues for many years, there is still room for improvement in terms of the results obtained. First of all, we need to fully determine the role of the spermatozoon because it tends to be thought of simply as the transporter of the father’s genetic material with no impact on later development. This idea has already been turned on its head and sperm does not only play a role in the fertilisation process. An abnormal spermatozoon can give rise to abnormal embryos and can even influence implantation failure. […]

2017-09-01T14:27:10+02:001 de September de 2017|0 Comments

Could it be implantation failure why I don’t get pregnant? Diagnosis in one day.

Achieving pregnancy when pregnancy does not come is one of the challenges the medical team at Instituto Bernabeu faces every day. One of the most important challenges of female infertility is implantation failure. The embryo does not get to nest in the maternal uterus or it does but the woman undergoes an early miscarriage, which produces a great frustration. The couple should put themselves as soon as possible in the hands of the specialist and not leave to chance or wait the passage of time to solve a situation that requires a personalized study.
Instituto Bernabeu Medical Director, Dr Rafael Bernabeu explains: “The causes of implantation failure are multiple, but contrary to the general opinion, patients believe they are causing the problem when, in fact, to a great extent the problem is embryonic”. Therefore, the medical centre global benchmark in reproductive medicine develops a study of the three patients: “The mother, the father and the embryo.” Twenty-five percent of embryo implantation failures cases, “do not have a clear cause” and in many cases, there is a combination of factors that can be combined, warns Dr Rafael Bernabeu. Not only are environmental and immunological factors, they are also due to the intake of certain foods and even to the cosmetics used. “We are exposed to tens of thousands of chemical substances and many generate disorders and among them may be the cause of repeated miscarriage and implantation failure,” says Dr Bernabeu. […]

2018-03-26T18:23:03+02:0027 de January de 2017|0 Comments

Using Magnetic Fields to Select Healthy Sperm: MACS (Magnetic Activated Cell Sorting)

It is well known that having the best possible sperm quality is important to the success of assisted reproduction techniques. To achieve this, the lab has to improve sperm quality based on its motility and morphology, selecting the sperm that is considered to be the best.
However in every ejaculate sperm with abnormal membranes are found, which are programmed to “die”. This process is called apoptosis, or programmed cell death.   Approximately 20% of sperm in subfertile patients are  thought to be in the process of “celular death”. […]

2016-09-22T12:18:09+02:002 de October de 2013|0 Comments

Unraveling the mysteries of ICSI (Intracytoplasmic sperm injection)

We’re dedicating this Instituto Bernabeu forum topic to a very common technique used in the human reproduction laboratory: ICSI or Intracytoplasmic sperm injection. We have prepared this explicative video on the topic, in which Dr. Jorge Ten simply explains what this technique involves, how it is performed, its indications, history and evolution, as well as our reproductive biology team’s efforts to perfect the results. We hope you like it! […]

2016-09-22T11:43:59+02:002 de May de 2013|1 Comment
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