Owing to sociocultural and economic factors, there has been a considerable increase in recent years in the number of men over the age of 35 who wish to have children. As a couple ages, the probability that they will experience reproductive problems increases. The negative effect of maternal age on fertility has been widely documented and we know that fertility diminishes drastically after the age of 39. Maternal aging is also associated with miscarriage, pregnancy complications, congenital anomalies and an increase in perinatal mortality.
However, few studies analyse the effect of paternal age on success after the application of assisted reproduction technology (ART) and the results they provide are contradictory. It is true that the male reproductive function is less vulnerable than the female where the aging process is concerned, as is demonstrated by the fact that many babies have been born spontaneously to fathers who are in their seventies or eighties. However, some associations have been found in specific studies that relate a negative effect of advanced paternal age with: […]