A patient can be classified as having poor response when the number of oocytes obtained during a cycle of in vitro fertilisation is under what was expected. The criteria generally used to label a patient as a poor responder is when 3 or fewer oocytes are retrieved and she has incredibly low ovarian reserve markers (fundamentally, AMH and AFC). […]
poor ovarian reserve
Fragile X syndrome is one of the most common causes of hereditary intellectual disability.
The gene responsible for the disease is known as FMR1 and it is found in the X sex chromosome. As a result, both the transmission and the severity of the disorder varies in each sex. As a general rule, men are said to suffer from it whilst women are said to transmit it.
There is a repeat region in the FMR1 gene (expansion) and its size determines whether or not the individual has the disorder or not, as indicated below. […]
Instituto Bernabeu focusses on providing personalised solutions, particularly in cases of patients with a difficult reproductive prognosis (low ovarian reserve and recurrent implantation failure (RIF)).
Carrying out a number of empirical tests and treatments has, on occasions, been put forward as an option in the case of patients suffering from recurrent implantation failure. The latter have proven to be of questionable efficacy and the former have proven to be of limited or no use.
One of the proposed strategies for patients with recurrent implantation failure (RIF) that is providing many of these cases with solutions, is IVF (in vitro fertilisation) with elective freezing and biopsies on all embryos so that the frozen embryos can later be transferred during a natural cycle. In other words, without any hormone treatment.
It is possible to recreate the conditions under which transfer takes place during treatment of this kind by carrying out a mock cycle and evaluating a series of parameters that can influence transfer success. […]