From an immunological point of view, pregnancy is a unique set of circumstances because a woman’s body has to ‘withstand something that is foreign to it’. The mother has to carry the embryo and, in order to do so, her immune system needs to accept co-existence with cells that are at least half foreign in origin. Using a […]
We are not yet fully aware of the exact reasons why sometimes a pregnancy happens and sometimes it does not. The embryo implantation process is an entire set of processes, many of which are unknown.
Based on the fact that the main factors that have an impact on implantation are the embryo and the female uterus, huge progress has been made […]
After ovulation, follicles transform into the corpus luteum or ‘yellow body’. Corpus luteum development depends on the luteinising hormone (LH) surge before ovulation and on the number of receptors for this gonadotropin in the granulosa cells and in the theca cells. Both types of cells go through significant changes in structure and composition and this turns the walls of the corpus […]
Whilst it is not part of the day-to-day routine at reproductive
medicine clinics, it is now increasingly common to have to transport biological
samples (oocytes, semen or embryos) from one clinic to another and even from
one country to another.
There can be several reasons for this such as the following:
couple wishes to continue their treatment in a […]
Nowadays, many couples have to turn to gamete donation in order
to make their dream of becoming parents come true. In cases such as these, the
couple tends to have common and understandable doubts about reproduction
treatment clinics’ processes for accepting gamete donors onto their banks.
Let us use this forum to explain the semen donor selection process at Instituto Bernabeu […]
Personalising courses of treatment is undoubtedly currently the
most important area of change in the field of medicine. A specific strategy should be designed
depending on each patient’s individual characteristics.
One of the key areas for developing personalised medical healthcare is the use of pharmacogenetics. A patient needs different doses or types of pharmaceutical drugs depending on certain genetic variations. […]
It is common knowledge that a seminogram is one of the basic tests that couples who are having issues getting pregnant. In other words, the male partner’s semen needs to be analysed in order to check certain parameters such as the quality of spermatozoa in ejaculate, their motility, their morphology and so on. The aim is to […]
The risk of contracting HIV during unprotected sexual intercourse is estimated to be between 0.5 and 1%. For serodiscordant couples (one partner is a carrier), trying for a child naturally can entail an elevated risk of transmission. In cases such as these, assisted reproduction techniques are an excellent choice for getting pregnant without the risk […]
Embryo fragmentation is a phenomenon that takes place in most embryos and its origin is not entirely clear. Some studies would seem to suggest that the fragments come from cell remains that have no nucleus or that they are the result of the decomposition of one or more cells from the embryo itself. The oocyte plays the most important role in fragmentation. Poor oocyte quality can lead to embryos that are highly fragmented. Embryo quality is determined by several characteristics such as the number of cells, their size or if the cell interior has an abnormality of any kind such as granularity or vacuolisation. However, one of the factors that has most impact on embryo quality is the extent of fragmentation. Based on the amount, in percentage, of space that it occupies, fragmentation is categorised into 4 types or degrees. […]