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What role does the immune system play in fertility?

From an immunological point of view, pregnancy is a unique set of circumstances because a woman’s body has to ‘withstand something that is foreign to it’. The mother has to carry the embryo and, in order to do so, her immune system needs to accept co-existence with cells that are at least half foreign in origin. Using a […]

2019-03-15T10:09:00+02:0015 de March de 2019|1 Comment

Uterine contractions: a challenge for embryo implantation

We are not yet fully aware of the exact reasons why sometimes a pregnancy happens and sometimes it does not. The embryo implantation process is an entire set of processes, many of which are unknown.

Based on the fact that the main factors that have an impact on implantation are the embryo and the female uterus, huge progress has been made […]

2019-02-28T09:54:40+02:001 de March de 2019|0 Comments

What is the corpus luteum?

After ovulation, follicles transform into the corpus luteum or ‘yellow body’. Corpus luteum development depends on the luteinising hormone (LH) surge before ovulation and on the number of receptors for this gonadotropin in the granulosa cells and in the theca cells.  Both types of cells go through significant changes in structure and composition and this turns the walls of the corpus […]

2019-03-04T12:41:29+02:0022 de February de 2019|0 Comments

Can patients manage embryo and gamete transportation?

Whilst it is not part of the day-to-day routine at reproductive
medicine clinics, it is now increasingly common to have to transport biological
samples (oocytes, semen or embryos) from one clinic to another and even from
one country to another.

There can be several reasons for this such as the following:

– The
couple wishes to continue their treatment in a […]

2019-02-08T10:17:41+02:008 de February de 2019|0 Comments

Exhaustive sperm donor selection and exclusion criteria

Nowadays, many couples have to turn to gamete donation in order
to make their dream of becoming parents come true. In cases such as these, the
couple tends to have common and understandable doubts about reproduction
treatment clinics’ processes for accepting gamete donors onto their banks.

Let us use this forum to explain the semen donor selection process at Instituto Bernabeu […]

2019-02-01T12:01:16+02:001 de February de 2019|0 Comments

Progress in treatment for patients with poor ovarian response

Personalising courses of treatment is undoubtedly currently the
most important area of change in the field of medicine. A specific strategy should be designed
depending on each patient’s individual characteristics.

One of the key areas for developing personalised medical healthcare is the use of pharmacogenetics. A patient needs different doses or types of pharmaceutical drugs depending on certain genetic variations. […]

2019-01-23T10:37:32+02:0025 de January de 2019|0 Comments

Temperature and Semen Quality

It is common knowledge that a seminogram is one of the basic tests that couples who are having issues getting pregnant. In other words, the male partner’s semen needs to be analysed in order to check certain parameters such as the quality of spermatozoa in ejaculate, their motility, their morphology and so on. The aim is to […]

2019-01-18T09:38:46+02:0018 de January de 2019|0 Comments

AIDS. Assisted reproduction is the best option

The risk of contracting HIV during unprotected sexual intercourse is estimated to be between 0.5 and 1%. For serodiscordant couples (one partner is a carrier), trying for a child naturally can entail an elevated risk of transmission. In cases such as these, assisted reproduction techniques are an excellent choice for getting pregnant without the risk […]

2019-01-11T10:57:28+02:0011 de January de 2019|0 Comments

Embryo fragmentation

Embryo fragmentation is a phenomenon that takes place in most embryos and its origin is not entirely clear. Some studies would seem to suggest that the fragments come from cell remains that have no nucleus or that they are the result of the decomposition of one or more cells from the embryo itself. The oocyte plays the most important role in fragmentation. Poor oocyte quality can lead to embryos that are highly fragmented. Embryo quality is determined by several characteristics such as the number of cells, their size or if the cell interior has an abnormality of any kind such as granularity or vacuolisation. However, one of the factors that has most impact on embryo quality is the extent of fragmentation. Based on the amount, in percentage, of space that it occupies, fragmentation is categorised into 4 types or degrees. […]

2018-12-17T11:07:30+02:0021 de December de 2018|0 Comments

The importance of embryo nutrition in achieving a successful cycle of in vitro fertilisation (IVF): metabolomics

One of the main limitations of assisted reproduction techniques are its embryo implantation failure rates. The implantation rate is the embryo’s ability to implant in the mother’s uterus. In other words, not all embryos are able to give rise to a pregnancy. Some have a greater chance of doing so than others. If it were possible to select embryos with the greatest ability to implant, it would be possible to improve assisted reproduction technique success rates. […]

2018-12-14T10:23:05+02:0014 de December de 2018|0 Comments
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