After ovulation, follicles transform into the corpus luteum or ‘yellow body’. Corpus luteum development depends on the luteinising hormone (LH) surge before ovulation and on the number of receptors for this gonadotropin in the granulosa cells and in the theca cells. Both types of cells go through significant changes in structure and composition and this turns the walls of the corpus […]
Nowadays, many couples have to turn to gamete donation in order
to make their dream of becoming parents come true. In cases such as these, the
couple tends to have common and understandable doubts about reproduction
treatment clinics’ processes for accepting gamete donors onto their banks.
Let us use this forum to explain the semen donor selection process at Instituto Bernabeu […]
Turner syndrome is a chromosomal condition caused by partial or total loss of one of the X chromosomes.
All human beings have 23 pairs of chromosomes and this is what is known as the karyotype. It is where all genetic information is stored. In other words, it is what determines our external appearance, our personal physical characteristics, how our organs work, whether or not we will have certain illnesses and so on. There are 22 pairs of numerical chromosomes ranging from 1 to 22 and one pair of sex chromosomes: X and Y. Women have two X chromosomes – one from their father and one from their mother. Men have one X chromosome – from their mother – and one Y chromosome – from their father. If, when a female embryo is generated, incorrect division leading to total or partial loss of the X chromosome takes place, this generates an abnormal karyotype that is characteristic of women with Turner syndrome. The syndrome, by definition, does not occur in males because they only have one X chromosome and cannot live unless this chromosome is present. […]
A patient can be classified as having poor response when the number of oocytes obtained during a cycle of in vitro fertilisation is under what was expected. The criteria generally used to label a patient as a poor responder is when 3 or fewer oocytes are retrieved and she has incredibly low ovarian reserve markers (fundamentally, AMH and AFC). […]
If you have been trying to get pregnant for a year or more without success, it’s time to search for an expert’s advice. […]
It is thought that about 20% of the reproductive problems are genetic or chromosomal. That is why the genetic testing is now an essential part of the fertility study carried out on couples who come to our centre for help to have children. […]
Achieving pregnancy when pregnancy does not come is one of the challenges the medical team at Instituto Bernabeu faces every day. One of the most important challenges of female infertility is implantation failure. The embryo does not get to nest in the maternal uterus or it does but the woman undergoes an early miscarriage, which produces a great frustration. The couple should put themselves as soon as possible in the hands of the specialist and not leave to chance or wait the passage of time to solve a situation that requires a personalized study.
Instituto Bernabeu Medical Director, Dr Rafael Bernabeu explains: “The causes of implantation failure are multiple, but contrary to the general opinion, patients believe they are causing the problem when, in fact, to a great extent the problem is embryonic”. Therefore, the medical centre global benchmark in reproductive medicine develops a study of the three patients: “The mother, the father and the embryo.” Twenty-five percent of embryo implantation failures cases, “do not have a clear cause” and in many cases, there is a combination of factors that can be combined, warns Dr Rafael Bernabeu. Not only are environmental and immunological factors, they are also due to the intake of certain foods and even to the cosmetics used. “We are exposed to tens of thousands of chemical substances and many generate disorders and among them may be the cause of repeated miscarriage and implantation failure,” says Dr Bernabeu. […]
When a fertility analysis in the male partner is limited to a seminogram or spermiogram, we only get a partial view of semen quality. A seminogram only provides us with information on the number and characteristics of sperm in the ejaculate (mobility, morphology…). It does not, however, tell us anything about other aspects such as sperm DNA integrity […]
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Clearly one of the most difficult situations a couple trying for children may have to face is pregnancy loss. Suffering is even greater when, prior to this, the couple has gone through fertility treatment such as in vitro fertilisation, insemination or egg donation.
Pregnancy loss is not always the result of an illness or underlying abnormality. It can be the response nature provides in order to block the development of an abnormal embryo. In fact, when the tissue from the pregnancy loss is examined, a large number of chromosomal abnormalities can be detected. […]
It is estimated that about 20% of reproductive problems are genetic or chromosomal type. That is why today genetic testing is an essential part of the fertility study in couples who come to our clinic looking for descendants.
For the diagnosis of fertility problems there is a set of genetic studies very useful in the assistance of couples with reproductive desire. Tests such as the karyotype in both partners, microdeletion of the Y chromosome in the male or the molecular study of fragile X syndrome in women are usually required tests to determine a possible genetic basis of fertility problems in couples. […]