instituto bernabeu

What is the corpus luteum?

After ovulation, follicles transform into the corpus luteum or ‘yellow body’. Corpus luteum development depends on the luteinising hormone (LH) surge before ovulation and on the number of receptors for this gonadotropin in the granulosa cells and in the theca cells.  Both types of cells go through significant changes in structure and composition and this turns the walls of the corpus […]

2019-03-04T12:41:29+02:0022 de February de 2019|0 Comments

Progress in treatment for patients with poor ovarian response

Personalising courses of treatment is undoubtedly currently the
most important area of change in the field of medicine. A specific strategy should be designed
depending on each patient’s individual characteristics.

One of the key areas for developing personalised medical healthcare is the use of pharmacogenetics. A patient needs different doses or types of pharmaceutical drugs depending on certain genetic variations. […]

2019-01-23T10:37:32+02:0025 de January de 2019|0 Comments

Temperature and Semen Quality

It is common knowledge that a seminogram is one of the basic tests that couples who are having issues getting pregnant. In other words, the male partner’s semen needs to be analysed in order to check certain parameters such as the quality of spermatozoa in ejaculate, their motility, their morphology and so on. The aim is to […]

2019-01-18T09:38:46+02:0018 de January de 2019|0 Comments

AIDS. Assisted reproduction is the best option

The risk of contracting HIV during unprotected sexual intercourse is estimated to be between 0.5 and 1%. For serodiscordant couples (one partner is a carrier), trying for a child naturally can entail an elevated risk of transmission. In cases such as these, assisted reproduction techniques are an excellent choice for getting pregnant without the risk […]

2019-01-11T10:57:28+02:0011 de January de 2019|0 Comments

Embryonic development: the embryo on day 1 (D1)

When an oocyte is in an optimum state of maturation, ovulation takes place. This is known as day 0 of development (D0) and fertilisation by a competent spermatozoon must take place during this period.

When the oocyte is fertilised, it is then known as a zygote and
we are now on D1 of development. Certain characteristics and essential
structures need […]

2019-01-04T09:51:56+02:004 de January de 2019|0 Comments

The latest in pre-implantation genetic diagnosis (PGD)

Pre-implantation genetic diagnosis(PGD) consists of studying chromosomalabnormalities and genetic abnormalities in the embryo prior to transfer to the mother. Itspurpose is to ensure that children are healthy and to bring thetransmission of a given condition to an end.

Significant progress that has revolutionised this area ofreproductive medicine has been made over the last few years and specificallywith regards to one type […]

2018-12-17T18:43:53+02:0028 de December de 2018|0 Comments

Embryo fragmentation

Embryo fragmentation is a phenomenon that takes place in most embryos and its origin is not entirely clear. Some studies would seem to suggest that the fragments come from cell remains that have no nucleus or that they are the result of the decomposition of one or more cells from the embryo itself. The oocyte plays the most important role in fragmentation. Poor oocyte quality can lead to embryos that are highly fragmented. Embryo quality is determined by several characteristics such as the number of cells, their size or if the cell interior has an abnormality of any kind such as granularity or vacuolisation. However, one of the factors that has most impact on embryo quality is the extent of fragmentation. Based on the amount, in percentage, of space that it occupies, fragmentation is categorised into 4 types or degrees. […]

2018-12-17T11:07:30+02:0021 de December de 2018|0 Comments

The importance of embryo nutrition in achieving a successful cycle of in vitro fertilisation (IVF): metabolomics

One of the main limitations of assisted reproduction techniques are its embryo implantation failure rates. The implantation rate is the embryo’s ability to implant in the mother’s uterus. In other words, not all embryos are able to give rise to a pregnancy. Some have a greater chance of doing so than others. If it were possible to select embryos with the greatest ability to implant, it would be possible to improve assisted reproduction technique success rates. […]

2018-12-14T10:23:05+02:0014 de December de 2018|0 Comments

Obesity and fertility

The extent of the issue
Obesity is a public health issue both in the general population and in women of childbearing age. The figures are a proof of this and, far from improving, the problem has been getting progressively worse over the last few years.
Maternal obesity in the United States of America was calculated to be 7% in 1980 and had risen up to 24% by 1999. If we take into account both obesity and excess weight, the available data indicates that the figures were 37.1% in 1999 and 40.5% in 2003.
The NHANES (National Health and Nutrition Examination Survey) reveals obesity figures (BMI or body mass index ≥ 30 kg/m2) in women of reproductive age (20 to 39 years of age) of 31.9%.
In other words, one in every three women of a fertile age is obese. […]

2018-12-07T10:06:37+02:007 de December de 2018|0 Comments

DNA fragmentation in sperm: TUNEL

When a couple fails to get pregnant or has an unsuccessful pregnancy, a number of tests performed on both partners is recommended. One of the basic tests in analysis of the male partner involves performing a seminogram or spermiogram that provides us with an initial indication of semen quality. This information can be supplemented with a sperm DNA fragmentation analysis, should this be considered necessary.
The DNA fragmentation test is a technique that supplements a study of the male factor in certain cases. […]

2018-11-28T09:56:53+02:0030 de November de 2018|0 Comments
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