From an immunological point of view, pregnancy is a unique set of circumstances because a woman’s body has to ‘withstand something that is foreign to it’. The mother has to carry the embryo and, in order to do so, her immune system needs to accept co-existence with cells that are at least half foreign in origin. Using a […]
The immune system plays a very important role in the health of human beings, acting as a defence barrier against harmful organisms or substances.
Immunology is a very complex area when trying to get pregnant or as a pregnancy progresses and it involves an elevated number of cell types and molecules that need to work in a coordinated and balanced manner. […]
Embryo implantation is the least well known phase of reproduction within the field of reproductive medicine. This fact is of special relevance if we also take into account that the human embryo is not very efficient when compared to other closely-related species in the evolution timeline.
We currently know that pregnancy is based upon three basic pillars: the embryo, the endometrium and the tolerance of the mother’s immune system. Not only is it essential that all three function correctly, but there needs to be optimum interaction between them. We have already covered the role of the embryo and the immune system in detail. Therefore, we will now concentrate on the endometrium and, more specifically, on studying endometrial receptivity. […]
Numerous factors are involved in making the amazing miracle of pregnancy possible. Many of them are very well understood whilst others, such as the immune system and its role in embryo implantation, given their importance, are still being studied and researched in depth. If the immune system is what protects the body against infection and diseases thanks to its defences, what role does it play in achieving pregnancy? […]
Couples who get pregnant, either naturally or through assisted reproductive techniques, are especially worried about the successful outcome of the pregnancy.
Unfortunately, some pregnancies end in miscarriage or fetal loss in the week 20 of pregnancy, when the fetus is not able to survive outside of the maternal uterus. […]
At some point in our lives, we have all tricked our mothers.
We are not referring to the white lies of our youth or our schoolyard antics. We are talking about the critical moment in our lives: when we were embryos.
Due to the fact that the embryo does not have the same proteins or make up as maternal tissue, it is a unique moment for the mother’s immune system. […]