During in vitro fertilisation processes, for the first few days of their lives, human embryos have to develop outside the mother’s body in special incubators. Temperature and pH conditions need to be optimum and embryos also need to have access to all the necessary ingredients in order to feed and, in doing so, meet their energy requirements. Culture media are used for this. […]
During the performance of assisted reproduction procedures, the best embryo is selected for transfer into the mother’s uterus. The selection is based on the “look” of the embryo shortly before transfer. As a matter of fact, waiting time normally stretches until day 5 of embryo culture in order to enhance the potential of the selected embryo and its synchronisation with the endometrium.
Sometimes the selection is favoured by performing a Comprehensive Chromosome Screening (PGS/PGT-A/CCS) test. Thanks to this technique, we can find out if an embryo has all the chromosomes in their exact number, in other words, if it is chromosomally normal. In this way, the selection is both morphological (external look) and chromosomal (internal look).
To be able to analyse the embryo we must first biopsy it (take a cell sample) without affecting its development and subsequent implantation. Biopsy techniques have been evolving until the process has been optimised. […]
When we perform an assisted reproduction cycle, we try to optimise the results as much as possible. Currently, the most physiological way of achieving this is with an embryo culture that reaches the blastocyst stage. […]
A patient with low response to the ovarian stimulation for IVF is probably the most significant challenge faced by professionals treating couples with fertility problems.