Improving embryo culture by mimicking the conditions generated during in vivo culture is a key contributor towards improving success rates in couples who turn to in vitro fertilisation in order to solve their sterility issue.
In vitro culture of human embryos has traditionally been carried out in incubators in a controlled atmosphere at 6% CO2 and 21% O2. However, based on studies carried out on different species of mammals, we know that these conditions do not match those found in vivo in the fallopian tubes and the uterus where oxygen tension ranges between 2 and 8%. […]