Dr. Ruth Morales

The advantages of comprehensive chromosome screening (PGS/PGT-A/CCS) in women of an advanced maternal age

Women currently seek guidance on reproduction at a much older age than they did some years ago. As a result, amongst the women who undergo fertility treatment, there is a significant group of women of an advanced age and their prognosis is poorer. This is a huge challenge for reproduction specialists. […]

2018-09-06T09:36:01+02:007 de September de 2018|0 Comments

Tobacco and semen quality

According to the World Health Organization (WHO), nowadays between 10 and 15% of couples have fertility issues and between 30 and 35% of the reasons for infertility can be found in the male partner. Therefore, improving semen quality is one of the main concerns amongst couples with reproduction issues. […]

2018-05-03T17:24:58+02:004 de May de 2018|0 Comments

Should embryos with chromosomal mosaicism be rejected?

When good quality embryos do not implant correctly or lead to pregnancy loss, in vitro fertilisation (IVF) does not provide us with the results we had hoped for. This is often because the embryo is a carrier of abnormal chromosomes. Fortunately, in our clinic, we have access to the very latest in embryo chromosome diagnosis techniques such as array CGH and next generation sequencing (NGS). We can use this technology to detect abnormalities in the embryo that will cause pregnancy loss or that will lead to the birth of a child with chromosomal abnormalities such as Down’s Syndrome, also known as trisomy 21. As such, we can use these techniques to select and transfer the embryos with the greatest chance of leading to the birth of healthy child. […]

2018-03-26T17:47:29+02:0025 de August de 2017|0 Comments

Using stem cells as the answer to ovarian failure: hope for the future or reality?

Significant progress has been made over the last few decades in the field of fertility in order for patients to be able to have children of their own. However, one of the greatest challenges in reproductive medicine is pregnancy in women with slim chances of obtaining their own eggs. For example, women with premature ovarian failure (in other words, egg loss at a young age) or, quite simple, women over the age of 40. […]

2017-07-21T08:55:55+02:0021 de July de 2017|0 Comments

Why does Comprehensive Chromosome Screening (PGS/PGT-A/CCS) by array-CGH reduce miscarriage rates?

Miscarriage rates in the general population with no fertility problems range around 15-20%. In other words, one out of every five couples who achieve pregnancy suffers a spontaneous miscarriage, and 5% of these couples suffer it more than once. Even when pregnancy is achieved with the help of assisted reproduction techniques, miscarriage rates do not vary. For this reason, it is important when couples come to our clinic seeking reproductive counselling to perform comprehensive testing and design an adequate protocol for their case to secure the best result, which is a healthy baby at home, minimising the chances of miscarriage. In order to do that, one should know that miscarriages and pregnancy losses are caused by different reasons (uterine problems, immunological problems, and so on), and yet in half the cases there are chromosomal abnormalities in the embryo that prevent pregnancies to progress, hence causing miscarriages. Normal embryos have two copies of each chromosome, one inherited from the father and the other from the mother, and the chromosomal anomalies they may suffer involve a change in the number of copies, producing an imbalance in their genetic load which might block embryo development. […]

2018-05-14T08:49:14+02:0012 de February de 2016|0 Comments

Chromosomal alterations in repeated miscarriages

Couples who get pregnant, either naturally or through assisted reproductive techniques, are especially worried about the successful outcome of the pregnancy.

Unfortunately, some pregnancies end in miscarriage or fetal loss in the week 20 of pregnancy, when the fetus is not able to survive outside of the maternal uterus. […]

2016-09-22T12:23:08+02:0018 de February de 2013|0 Comments
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