How can the best spermatozoon for fertilising an egg be selected?

Selection of the spermatozoon capable of fertilising an egg and generating a viable embryo is a subject that has been covered in a great number of studies aiming to provide this question with an answer.
Although assisted reproduction techniques have been used for dealing with fertility issues for many years, there is still room for improvement in terms of the results obtained. First of all, we need to fully determine the role of the spermatozoon because it tends to be thought of simply as the transporter of the father’s genetic material with no impact on later development. This idea has already been turned on its head and sperm does not only play a role in the fertilisation process. An abnormal spermatozoon can give rise to abnormal embryos and can even influence implantation failure. […]

2017-09-01T14:27:10+02:001 de September de 2017|0 Comments

What is adenomyosis?

Adenomyosis is defined as an abnormal presence of endometrial tissue inside the muscular lining of the uterus.
Adenomyosis is not a well-known condition because diagnosis is not easy. Clinical expression can range from no symptoms whatsoever to heavy, lengthy periods and dysmenorrhoea. […]

2017-08-11T10:06:22+02:0011 de August de 2017|0 Comments

New examination aimed at testing couples with recurrent implantation failure

Instituto Bernabeu focusses on providing personalised solutions, particularly in cases of patients with a difficult reproductive prognosis (low ovarian reserve and recurrent implantation failure (RIF)).
Carrying out a number of empirical tests and treatments has, on occasions, been put forward as an option in the case of patients suffering from recurrent implantation failure. The latter have proven to be of questionable efficacy and the former have proven to be of limited or no use.
One of the proposed strategies for patients with recurrent implantation failure (RIF) that is providing many of these cases with solutions, is IVF (in vitro fertilisation) with elective freezing and biopsies on all embryos so that the frozen embryos can later be transferred during a natural cycle. In other words, without any hormone treatment.
It is possible to recreate the conditions under which transfer takes place during treatment of this kind by carrying out a mock cycle and evaluating a series of parameters that can influence transfer success. […]

2017-11-29T10:16:08+02:0030 de June de 2017|0 Comments

Endometritis: What is it? How can it be detected? How can it be cured?

 Endometritis is inflammation of the endometrium. That is, inflammation of the internal lining of the uterus cavity where embryo implantation takes place.
 Severe endometritis is an uncommon gynaecological emergency which is generally iatrogenic following placenta retention after birth or pregnancy loss. Patients in this situation have a number of symptoms which are typical of an infection. For example, fever, purulent discharge, general discomfort and so on.  If it is not treated, then the situation can lead to a generalised infection. […]

2017-03-23T14:53:21+02:0023 de March de 2017|0 Comments

Embryo transfer in natural cycles

In an in vitro fertilization, embryo transfer takes place in the same cycle in which the ovaries are stimulated and the embryos are generated. However, on many occasions, this is not ideal. The development of several follicles in the ovaries, upon receipt of various stimulus from different follicles, can deconstruct the endometrium and disrupt its implantation capacity. […]

2017-03-13T18:29:59+02:0013 de March de 2017|0 Comments

Personalised counselling unit. Don’t let your doubts hold you back. We’re there to make you feel at ease

Behind our on-line consultation system, there is a team of trained personnel. The team is ready to help users and make them see that the concerns amongst people who are looking for an answer to their doubts or worries, are also our concerns. Instituto Bernabeu has a Personalised Counselling Unit. Its team of experts has been trained to clear up the doubts which people understandably have when they are thinking about beginning treatment, when they wish to compare opinions, when they are looking for help regarding how much treatment will cost or when they have gynaecological-related doubts about assisted reproduction.  […]

2017-02-17T15:08:10+02:0017 de February de 2017|0 Comments

Could it be implantation failure why I don’t get pregnant? Diagnosis in one day.

Achieving pregnancy when pregnancy does not come is one of the challenges the medical team at Instituto Bernabeu faces every day. One of the most important challenges of female infertility is implantation failure. The embryo does not get to nest in the maternal uterus or it does but the woman undergoes an early miscarriage, which produces a great frustration. The couple should put themselves as soon as possible in the hands of the specialist and not leave to chance or wait the passage of time to solve a situation that requires a personalized study.
Instituto Bernabeu Medical Director, Dr Rafael Bernabeu explains: “The causes of implantation failure are multiple, but contrary to the general opinion, patients believe they are causing the problem when, in fact, to a great extent the problem is embryonic”. Therefore, the medical centre global benchmark in reproductive medicine develops a study of the three patients: “The mother, the father and the embryo.” Twenty-five percent of embryo implantation failures cases, “do not have a clear cause” and in many cases, there is a combination of factors that can be combined, warns Dr Rafael Bernabeu. Not only are environmental and immunological factors, they are also due to the intake of certain foods and even to the cosmetics used. “We are exposed to tens of thousands of chemical substances and many generate disorders and among them may be the cause of repeated miscarriage and implantation failure,” says Dr Bernabeu. […]

2018-03-26T18:23:03+02:0027 de January de 2017|0 Comments

What information does a FISH procedure on spermatozoa provide us with?

When a fertility analysis in the male partner is limited to a seminogram or spermiogram, we only get a partial view of semen quality. A seminogram only provides us with information on the number and characteristics of sperm in the ejaculate (mobility, morphology…). It does not, however, tell us anything about other aspects such as sperm DNA integrity […]

2018-03-26T17:56:49+02:0020 de January de 2017|0 Comments

Progesterone and its role in reproduction

What is progesterone? Just a simple look at the word itself gives us an idea of what its functions are. PROGESTERONE: the hormone which facilitates pregnancy. This is a good point from which to start out.
Progesterone plays an essential role in pregnancy and it has many and varied effects. It is a natural substance which is secreted from the ovaries following ovulation and continues throughout the second half of the menstrual cycle. Progesterone ensures that a woman’s uterus is receptive and, when production is insufficient, the embryo does not implant correctly or runs a high risk of leading to a miscarriage. It also relaxes the muscles in the uterus, making it better suited for the early days of pregnancy. […]

2016-11-17T18:41:53+02:0018 de November de 2016|0 Comments

Implantation failure and repeated miscarriage. Treatment options

Successfully treating implantation failure and recurrent pregnancy loss is undoubtedly a challenge for doctors and for patients.

It is an area on which we continuously focus research at Instituto Bernabeu and, whilst we are far from finding a solution to all problems, the number of couples we are able to successfully treat is forever increasing.

An approach which does not take all 3 parties into account – the female, the male and the embryo – is incomplete. When evaluation only takes the couple into account, the reason behind the issue is only determined in under 20% of all cases. […]

2020-03-12T10:47:54+02:0015 de November de 2016|0 Comments
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