Instituto Bernabeu takes 16 items of scientific research work to the Spanish Fertility Society congress

May, 21st 2018

Instituto Bernabeu took a total of 16 pieces of research work to the 32^nd edition of the Spanish Fertility Society (SEF) National Congress. This is a significant quantity of work and, at the group of reproductive medicine clinics, research is an intrinsic part of its activity that is also put into practice during day-to-day provision of healthcare.

Eleven of the lines of research were presented as oral communications over the course of the event held between 16^th and 18^th May in Madrid’s convention centre where experts in reproductive medicine met.

Amongst the work presented by the Instituto Bernabeu Group, the importance of the use of next generation sequencing techniques that can detect chromosomal abnormalities with a great deal of precision was highlighted. Another area of research discovered that patients with poor ovarian response have a different distribution in the follicle-stimulating hormone genotype. Poor ovarian response is one field in which Instituto Bernabeu is a leader both in research and in clinical application of its research and improvements.

The fact that the clinic has in-house genetics and molecular biology laboratories means that the Instituto Bernabeu group of clinics can carry out very wide-ranging and in-depth research work such as the success of in vitro fertilisation treatment (IVF) following analysis of mitochondrial DNA in blastocysts. The clinic also presented research in which embryo comprehensive chromosome screening (CCS) is essential.

Instituto Bernabeu also presented a further five items of research work as posters. These included ‘The impact of oocyte maturity and the fertilisation rate on cycles with donated oocytes’, ‘Poor reserve: is it worth giving it a go?’ and another piece of work on the aneuploidy blastocyst rate and mosaicism following random ovarian stimulation.

Scientific and social updates in the field of reproductive medicine are highlighted at the congress and Instituto Bernabeu was present at this edition in the event on personalisation of ovarian stimulation. He gave a presentation entitled ‘Progress of treatment: follitropin delta.’ The gynaecologist, who is an expert in poor ovarian reserve, also participated in the debate entitled ‘Genetics: the breakthrough of genetics in the field of reproductive medicine.’

Dr Jorge Ten, Director of the Embryology Unit at Instituto Bernabeu and expert in molecular biology, also participated in another round table debate at the congress dealing with invasive and non-invasive embryo selection.

Each year, the Instituto Bernabeu Group attends this leading national fertility congress. The clinic presents the most important aspects of its research work that help to improve this science and have a positive impact on patient well-being and personalisation of treatment.

The research work presented:

ORAL Los embriones portadores de mosaicismo segmentario tienen una tasa de embarazo similar a los embriones euploides. Ruth Morales; Belén Lledó; José Antonio Ortiz; Adoración Rodríguez-Arnedo; Ll. Aparicio; Rafael Bernabeu.
ORAL Las pacientes con baja respuesta ovárica presentan una distribución diferente en el genotipo del receptor de hormona folículo estimulante (FSHR). Yasmina Ben-Aicha Gonzalez, J. Ll. Aparicio; Andrea Bernabeu; Juan Carlos Castillo; Lydia Luque; Belén Lledó; José Antonio Ortiz; Rafael Bernabeu.
ORAL La sensibilidad ovárica como nuevo biomarcador en reproducción asistida. Belén Moliner; Ll. Aparicio; Jaime Guerrero; Juan Carlos Castillo; Andrea Bernabeu; Francisco Sellers; Jorge Ten; Rafael Bernabeu.
ORAL Uso de medicamentos en condiciones diferentes a las autorizadas dentro de un programa de Fecundación in Vitro: revisión de los aspectos legales y experiencia de uso en pacientes con baja respuesta ovárica. Tamara Ruiz; Miriam Aula; Carmen Fernández; Eva García; Eva Valencia; Sandra Ogallar; Ll. Aparicio; Rafael Bernabeu.
ORAL Análisis completo del ADN mitocondrial (ADNmt) en blastocistos y su relación con el éxito de los tratamientos de FIV. Belén Lledó; José Antonio Ortiz; Ruth Morales; Elena García; Jorge Ten; Andrea Bernabeu; Ll. Aparicio; Rafael Bernabeu.
ORAL ¿Es útil la administración de heparina para mejorar el pronóstico en casos de abortos de repetición y/o fallos de implantación cuando el perfil de trombofilias y/o inmune no está alterado Ana Fabregat; L. Soria Moya; José Antonio Ortiz; Jaime Guerrero; Eva García; Azahara Turienzo; Belén Lledó; Rafael Bernabeu.
ORAL Las aneuploidías embrionarias que afectan a segmentos cromosómicos son más frecuentes en mujeres jóvenes. José Antonio Ortiz; Ruth Morales; Belén Lledó; Azahara Turienzo; Jorge Ten; Andrea Bernabeu; Ll. Aparicio; Rafael Bernabeu.
ORAL Los análisis de microbioma vaginal y endometrial se ven afectados por la región del rRNA16s estudiada. María Del Carmen Díaz; Andrea Bernabeu; Belén Lledó; José Antonio Ortiz; Ruth Morales; Jorge Ten; Ll. Aparicio; Rafael Bernabeu.
ORAL Implicación del personal de enfermería en los tratamientos de reproducción asistida ¿Cuál es la opinión de los pacientes? Rebecca Nataloni; Celinda Benítez; Miriam Aula; Tamara Ruiz; Ángela Álvarez; Joaquin Ll. Aparicio; Rafael Bernabeu.
ORAL ¿Existe correlación entre la calidad morfológica de la masa celular interna y del trofoectodermo con las tasas de aneuploidía y mosaicismo embrionario? Laura Cascales; Leyre Herrero; Elena Fernández; José Antonio Ortiz; Ll. Aparicio; Jorge Ten; Rafael Bernabeu.
ORAL Influencia del tipo de cultivo embrionario y láser empleado en la biopsia sobre la aparición de embriones mosaico. Laura Martí; Jorge Ten; José Antonio Ortiz; Adoración Rodríguez-Arnedo; Jaime Guerrero; Andrea Bernabeu; Ll. Aparicio; Rafael Bernabeu.
e-POSTER Reproductive epidemiology, socio-cultural aspects and health economy .Expert consensus for primary management of reproductive health: a Delphi study.
POSTER ¿Cuál es la mejor estrategia para realizar un ciclo de diagnóstico genético preimplantacional para aneuploidías? Jorge Ten; José Antonio Ortiz; Jaime Guerrero; Adoración Rodríguez-Arnedo, Belén Lledó, Andrea Bernabeu, Ll. Aparicio, Rafael Bernabeu
e-POSTER ¿Cómo influye la tasa de madurez ovocitaria y la tasa de fecundación en los ciclos de donación de ovocitos? Leyre Herrero; Elena Fernández; Laura Cascales; José Antonio Ortiz; Jaime Guerrero; Ll. Aparicio; Jorge Ten; Rafael Bernabeu.
e-POSTER Tasa de blastocistos aneuploides y mosaicismo tras estimulación ovárica aleatoria. Autor principal: Jaime Guerrero; José Antonio Ortiz; Jorge Ten; Adoración Rodríguez-Arnedo; Andrea Bernabeu; Ll. Aparicio; Rafael Bernabeu.
POSTER Baja reserva ovárica, ¿merece la pena intentarlo? María Antonia López; Lydia Luque; Iván Ochando; Nuria Ruiz; José Antonio Ortiz; Joaquín Ll. Aparicio; Rafael Bernabeu.