Homologous Intrauterine Insemination

Homologous Intrauterine Insemination in Spain

Homologous Intrauterine insemination is a procedure widely used for treating several reproductive disorders. It should not be confused with In Vitro Fertilisation (IVF), as the goal of IUI-H is to have fertilisation take place naturally within the Fallopian tubes. The patient does not have to rest or interrupt her daily routine afterwards.

In Spain, this treatment is controlled by legislation that requires the couple to formally give their informed consent authorising the clinic to carry out analyses to rule out serious diseases that may effect the health of any future offspring (such as syphilis, different types of hepatitis, HIV).

Homologous Intrauterine Insemination

The technique consists of several stages:

1. Ovulation Stimulation

Every month, the ovary starts developing hundreds of oocytes (the cell that is fertilised by the spermatozoid producing the embryo). Only one, or rarely two, will mature, which provokes ovulation or the release of the cell by the ovary. At the same time, the Fallopian tube embraces the ovary and collects the oocyte. The spermatozoid placed in the vaginal passage during intercourse must then reach the oocyte in the Fallopian tube. Ovarian stimulation ensures that the oocytes are developed properly and it synchronizes ovulation with the moment of insemination.

To achieve this, the patient will receive treatment with the following characteristics:

  • Medication must be adjusted precisely to your individual response: every woman responds differently and even the patient’s subsequent cycles may require different doses.
  • It is essential to have regular check-ups of the ovaries in order to reach the ideal response. These checks are done using vaginal ultrasound scans and occasionally blood tests. This way, we can ensure that the dose is correct. An insufficient dose could result in a poor response. On the other hand, an excessive dose could produce multiple ovulations, creating the risk of a multiple pregnancy.

Normally, between two and four visits are required throughout the cycle. These check-ups allow us to predict the moment of ovulation, helping us to properly time the moment of insemination. If the ovarian response is incorrect, for instance, the insemination would not take place in order to avoid multiple ovulations.

2. Sperm capacitation

On the scheduled day of insemination, the male partner leaves a sample of his ejaculate as per given instruction. In the laboratory, the best spermatozoids are isolated and then their fertilisation capacity is increased by incubating them in media culture, which takes between two and four hours. Once complete, insemination takes place.

Insemination: Homologous Intrauterine Insemination in spain

Insemination consists of placing the improved sperm inside the uterus. The procedure only needs be done once per cycle, as we will know the exact moment to inseminate thanks to the prior check-ups.

It is a fast and totally painless technique that uses a thin plastic catheter, which allows us to place the sperm close to the orifice of the Fallopian tube.

Therefore, since we are provoking the ovulation of mature oocytes and the best spermatozoids are chosen and placed inside the uterus, we drastically increase the likelihood that the two cells will find each other and fertilise, creating a pregnancy.

After insemination, the patient can calmly return to her daily activities.

The cycle success rate in insemination is between 14%-20%.

We rarely recommend more than three cycles because most pregnancies using this technique occur in the first cycle. If fertilisation does not take place, an appointment is arranged so that the patients can be advised by our Reproductive Medicine Committee. Our medical team meets to evaluate the clinical case and inform the couple of their options.

The possibility of gestation is the same in every cycle. The rate of multiple pregnancies is reduced thanks to a correct control in 8%. (Published by our team in May 2004.Fertility-Sterility magazine).

Once pregnancy has been confirmed, it will evolve in the same way as any other natural pregnancy.

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Instructions for preparing and administering GONAL: medication for stimulating oocyte growth.

Instructions for preparing and administering PUREGÓN: medication for stimulating oocyte growth.

Instructions for preparing and administering FOSTIPUR: medication for stimulating oocyte growth.

Instructions for preparing and administering OVITRELLE: medication for inducing ovulation.

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