Preimplantation Genetic Diagnosis (PGD) is the study of chromosomal and genetic abnormalities in embryos before they are transferred to the mother’s uterus by an In Vitro Fertilisation (IVF) technique. It seeks to ensure healthy offspring and stop transmission of a given disease. […]
Preimplantation Genetic Diagnosis (PGD) is a tool designed to “get to know” the embryos genetically before they are transferred into the mother’s uterus. Thanks to this technique, we can study their chromosome count and find out if they are carriers of a hereditary disease. This information helps us to select the embryos that will produce healthy babies. Yet, how can we find that information?
Today, the only way to find genetic information about embryos is by performing an embryo biopsy. What does embryo biopsy involve?
To explain the biopsy procedure we should keep in mind that our point of departure is EMBRYOS. Embryos are retrieved after performing an assisted reproduction cycle, preferably by Intracytoplasmic Sperm Injection (ICSI), and their development is assessed during the culture period until day 3 or day 5. […]
Assisted Human Reproduction is undoubtedly an area with ethical and moral implications. There are common issues that arise with the generation of new embryos when a couple undergoes ART and with transfers of previously frozen embryos. Some of the most frequent issues are: embryo manipulation and genetic diagnosis; the use of donor gametes and the possible coexistence of their legal children with the biological ones in the future; the option of discarding embryos by parents for no other purpose when they don’t wish to donate them to other couples with reproductive problems or for research purposes; the age of women accessing ART, along with a long list of legal, ethical and moral issues pertinent to each assisted reproduction centre. […]
Multiple pregnancy is, along with ovarian hyperstimulation, the most significant complication in fertility treatments.
Most couples that go through assisted reproduction techniques consider multiple pregnancies to be desirable or the lesser evil. However, pregnancies of twins and even more so triplets are associated with a series of complications that challenge the pregnancy ending in the birth of a healthy baby. Let us not forget that the birth of a healthy baby is the only objective of assisted reproductive techniques. […]
We’re dedicating this Instituto Bernabeu forum topic to a very common technique used in the human reproduction laboratory: ICSI or Intracytoplasmic sperm injection. We have prepared this explicative video on the topic, in which Dr. Jorge Ten simply explains what this technique involves, how it is performed, its indications, history and evolution, as well as our reproductive biology team’s efforts to perfect the results. We hope you like it! […]
New technologies are making remarkable progress in the diagnosis of fertility. The latest development that has been incorporated into the range of diagnostic techniques is called array-CGH.
This new genetic test allows us to analyze our cells’ DNA to limits that years ago we would have considered pure science fiction.
The human genome is made up of 46 chromosomes: 23 from the father and 23 from the mother. All of our organism’s genetic information is stored in these chromosomes. The excess or defect of any chromosome region may be responsible for certain diseases or fertility problems, such as implantation failure or recurrent miscarriages. […]
Preimplantation Genetic Diagnosis (PGD) is a new technique used in Reproductive Medicine and is one of the main sources of innovation and research. PGD allows embryos to be selected from assisted reproduction cycles and tested for certain genetic or chromosomal abnormalitybefore being transferred to the womb.
At Instituto Bernabeu, we have developed a specific programme with protocols designed to treat repeated miscarriages and unsuccessful assisted reproduction treatments through the multidisciplinary approach that allows us to diagnose and therefore overcome these problems.
Cystic fibrosis is a chronic and progressive disease that appears in early childhood and affects many organs in the body, (such as the lungs, intestines, pancreas, liver…). The disease causes thick mucus production, which leads to blockages and infections.