Calculating ovulation: the best time to get pregnant

One of the most frequently asked questions among couples is how to calculate the most fertile days of the cycle and when ovulation will take place in order to make this coincide with sexual intercourse. Calculating it is simple in the case of regular, 28-day cycles. […]

Poor Ovarian Response: progress in genetics

Ovarian stimulation is key in results obtained as a results of assisted reproduction techniques. Daily clinical practice shows us that ovarian response can vary substantially from one woman to another. With this in mind, we can diagnose a patient as a poor responder when three eggs or less are obtained.
This situation affects more and more women every day. They require specialised healthcare and personalised protocols and, in response to this need, Instituto Bernabeu has a Poor Ovarian Response Unit that deals with multidisciplinary diagnosis and treatment.
For patients under this category, obtaining one or more eggs can mean the difference between failure and pregnancy and this makes any steps taken to increase the number of available eggs absolutely essential. […]

Recurrent pregnancy loss: an issue that does have a solution

Clearly one of the most difficult situations a couple trying for children may have to face is pregnancy loss. Suffering is even greater when, prior to this, the couple has gone through fertility treatment such as in vitro fertilisation, insemination or egg donation.
Pregnancy loss is not always the result of an illness or underlying abnormality. It can be the response nature provides in order to block the development of an abnormal embryo. In fact, when the tissue from the pregnancy loss is examined, a large number of chromosomal abnormalities can be detected. […]

Motherhood at the age of 40

Trying for a child after 40 years of age is a growing trend in today’s society and not only in Spain, but in Europe, too. Professional, personal and social reasons have joined together in making women decide to put motherhood off for longer and longer. But nature takes its course and each woman is only fertile for a certain period of time and this can affect her chances of getting pregnant. In the light of such a common situation, what do we need to take into account? What is the key role played by experts in health and fertility?
Since 2002, the average age at which a woman has her first child has increased two years. Whilst in 2002 the average age was 29, the Spanish National Statistics Institute’s most recent figures show that it has now gone up to 31 and that there is an upward trend.  This increase in the age at which women have their first child is similar to the increase in other European Union countries where an increase of around two years has been registered. Figures show that women are waiting until they are near their 40s and even older before trying to get pregnant. […]

State of the art technology in preimplantation embryo diagnosis: Array-CGH

Preimplantation Genetic Diagnosis (PGD) is the study of chromosomal and genetic abnormalities in embryos before they are transferred to the mother’s uterus by an In Vitro Fertilisation (IVF) technique. It seeks to ensure healthy offspring and stop transmission of a given disease. […]

Specialised healthcare in the Instituto Bernabeu endometriosis unit

Endometriosis is the presence outside the uterus of tissue from the uterus known as the endometrium (the lining that covers the uterus where the embryo embeds). It can implant anywhere in the body, except the spleen. […]

What does embryo biopsy involve?

Preimplantation Genetic Diagnosis (PGD) is a tool designed to “get to know” the embryos genetically before they are transferred into the mother’s uterus. Thanks to this technique, we can study their chromosome count and find out if they are carriers of a hereditary disease. This information helps us to select the embryos that will produce healthy babies. Yet, how can we find that information?
Today, the only way to find genetic information about embryos is by performing an embryo biopsy. What does embryo biopsy involve?
To explain the biopsy procedure we should keep in mind that our point of departure is EMBRYOS. Embryos are retrieved after performing an assisted reproduction cycle, preferably by Intracytoplasmic Sperm Injection (ICSI), and their development is assessed during the culture period until day 3 or day 5. […]

Co-mother registration for lesbian couples

Last July, Act 19/2015 on administrative reforms in the field of Justice Administration and Civil Registration made changes to article 7.3 of Act 14/2006 on human assisted reproduction techniques, making it clearer than before and providing for equality between heterosexual and lesbian couples.
The new law states that ‘When a woman is married to another woman and there has been no legal or de facto separation, the latter, in accordance with the Law on Civil Registry, may agree to her parentage of the child born unto her partner.’ […]

A revolution in genetics: next generation DNA sequencing

In the year 2000, human sequencing was achieved following 10 years of scientific work and now, thanks to next generation DNA sequencing, we are able to get to know a human genome in the space of just one week. It is still not possible, however, to access 100% of the genetic information contained within an embryo, the true origin of human life. But scientific progress is unstoppable and with this new technique a new range of promising options for genetics, for fertility and for life have opened up.
According to researchers, the possibilities which DNA sequencing offers are revolutionary and huge. Despite being at a very initial stage in which only the tip of the next generation sequencing iceberg has been uncovered, the number of uses is so varied that determining how to manage everything this technique implies will, in fact, be the future’s biggest challenge.
For the time being, thanks to human sequencing, nowadays “there is greater power of analysis and this facilitates many things and very significant possibilities”, explains the scientist and molecular biology and genetics investigator at Instituto Bernabeu, José Antonio Ortiz. The new technique, which can only be carried out in leading international clinics such as IB, “has revolutionised genetics. Genetic studies are now much quicker.’ […]

By |5 de February de 2016|Fertility, Genetics, Gynaecology, News, Reproductive biology|0 Comments

Choosing a fertilisation technique when oocyte counts are poor. IVF or ICSI?

A low ovarian response is an increasingly common situation for clinicians. It is mainly associated with delayed motherhood and, accordingly, with lower ovarian reserves. In this type of patients, the number of oocytes retrieved after puncture is normally limited. In this situation, choosing the most adequate fertilisation technique, conventional IVF or Intracytoplasmic Sperm Injection (ICSI), may stir a little controversy (of course, provided that the sperm quality and the medical history lead us to consider conventional IVF as a reasonable option). […]