What is a spermatid?

Spermatozoa production takes place in the testicular seminiferous tubules and the process is known as spermatogenesis.  At the end of this process, a germ cell generates 4 mature spermatozoa which will survive in the human body for between 62 and 75 days.  The final stage in spermatogenesis, known as spermiogenesis, is a cell differentiation and maturation process consisting of the change from spermatids to spermatozoa.  As can be seen in the picture, the spermatids develop from secondary spermatocites and have already undergone Meiosis I and II division. They have a normal set of chromosomes (haploid) which means that fertilisation of a mature egg can take place. Therefore, and despite the fact that they are immature cells, they can be used in assisted reproduction techniques using ICSI when there are no mature sperm in samples taken from the ejaculate or testicles. […]

Premature menopause

We understand the menopause as a complete end to menstruation. It is a retrospective diagnosis (looking back) and, as such, the menopause is said to have taken place when a year has gone by since the last period and, during that time, there have been no instances of menstrual bleeding.

It generally takes place at around 50 years of age and is linked to the number of eggs in the ovary.

Depending on a woman’s age, it can be: […]

How are seminograms interpreted?

A seminogram, or semen analysis, is a basic analysis of a semen sample with the aim of determining semen quality. In order to carry out the analysis correctly, the patient needs to refrain from sexual intercourse for a period of 3 to 5 days. That is, he must not ejaculate during that period and the sample must be obtained by means of masturbation.
The most relevant parameters evaluated in a semen sample include: […]

By |2016-12-13T19:08:46+00:0016 de December de 2016|Fertility, News, Reproductive biology, Urology|0 Comments

A negative beta hCG test. Now what?

What happens following the wait (‘the beta hCG wait’) which generates so much anxiety whilst, at the same time, creating the hope that our lives may be changed forever when, in the end, the result is negative?
Many patients say that the absence of symptoms meant that they knew what was coming; others were also expecting the worst because they had begun to bleed prior to getting the result of the analysis.
It’s important to point out that the presence or absence of ‘symptoms’ which women associate with pregnancy are not a means of diagnosis. It’s also important to clarify that vaginal bleeding of varying intensity is not infrequent prior to the programmed pregnancy test date and this does not necessarily mean that the result will be negative. Indeed, the results obtained from an analysis of the pregnancy hormone in blood is the only reliable proof available. A urine analysis is also an option but needs to be carried out a little later on and is not one hundred percent reliable. […]

What is a hydrosalpinx and how will it affect my fertility?

The tubes connecting the ovaries and the uterus are known as the Fallopian tubes (or uterine tubes). These structures play an essential role in natural reproduction and are responsible for receiving the egg each month and, furthermore, it is here that the union between egg and sperm takes place (fertilisation). They also enable the resulting embryo to be transported to the uterus which is where pregnancy will take place.
A hydrosalpinx is the result of an obstruction at the far ends of the Fallopian tubes which leads to the area becoming filled with liquid. This can lead to the Fallopian tubes becoming very swollen and distended, resulting in a ‘sausage-like’ appearance. In many cases, the obstruction and the liquid that has accumulated impair correct functioning of the Fallopian tube: semen does not travel up, the egg is not received by the tube and fertilisation does not take place, making achieving a natural pregnancy complicated (particularly so if both Fallopian tubes are affected). Alternatively, a hydrosalpinx can lead to pregnancy occurring within the tubes themselves (ectopic pregnancy). […]

Teratozoospermia and male infertility

Teratozoospermia is an increase in the percentage of abnormal sperm in a sperm sample and it is identified by means of a seminogram or semen analysis.
According to the criteria in the 5th edition of the World Health Organisation (WHO), 2010 manual, a man has teratozoospermia when the percentage of normal spermatozoa in the ejaculate is below 4%.
Defects in sperm […]

Progesterone and its role in reproduction

What is progesterone? Just a simple look at the word itself gives us an idea of what its functions are. PROGESTERONE: the hormone which facilitates pregnancy. This is a good point from which to start out.
Progesterone plays an essential role in pregnancy and it has many and varied effects. It is a natural substance which is secreted from the ovaries following ovulation and continues throughout the second half of the menstrual cycle. Progesterone ensures that a woman’s uterus is receptive and, when production is insufficient, the embryo does not implant correctly or runs a high risk of leading to a miscarriage. It also relaxes the muscles in the uterus, making it better suited for the early days of pregnancy. […]

Implantation failure and repeated miscarriage. Treatment options

Successfully treating implantation failure and recurrent pregnancy loss is undoubtedly a challenge for doctors and for patients.

It is an area on which we continuously focus research at Instituto Bernabeu and, whilst we are far from finding a solution to all problems, the number of couples we are able to successfully treat is forever increasing.

An approach which does not take all 3 parties into account – the female, the male and the embryo – is incomplete. When evaluation only takes the couple into account, the reason behind the issue is only determined in under 20% of all cases. […]

14th November, World Diabetes Day. Your Gynecological Care

On the occasion of the World Diabetes Day, we have dedicated today’s post. At Instituto Bernabeu, our different departments are prepared for the care of patients with this condition. The diabetic patient needs special care, so you should know all the information about your gynaecological and reproductive health, as well as the most appropriate method […]

FSH hormone levels

Follicle-stimulating hormone (FSH) is produced by the pituitary gland situated at the base of the brain. It is released from this gland into the bloodstream and plays an essential role with regards to the ovaries. Its purpose is to stimulate follicle growth and selection and it also plays a role in maturing the egg which will later be released during ovulation.
In cases of ovarian insufficiency, the pituitary gland attempts to compensate for this by increasing FSH secretion. This happens in a physiological manner during the menopause and, as a result, women going through this stage have FSH levels which are far above those in women of childbearing age.

If abnormally high levels of FSH (>10 lU/L) are detected at a young age, this can be a suggestion of low ovarian reserve which reduces the possibility of getting pregnant naturally. […]