BETA pregnancy confirmation after IVF or other reproductive techniques

May 30 2011

What is a Beta?

The determination of the levels of the hormone beta-hCG in blood. The hormone produces the embryo and passes to the mother via the placenta. This is the first measurable sign of embryo implantation.

When can the Beta be performed?

During an In Vitro Fertilisation treatment, it is performed 13 or 14 days after the egg collection. When it comes to Egg Donation treatments or frozen embryo transfers, it is taken 13 or 14 days after starting the administration of progesterone (Utrogestan ®, Progeffik ®, Cyclogest ®).

What value of Beta is considered normal?

This depends on when the analysis is performed. If it is taken 13 days after the egg collection, a value of 30 mIU / ml is considered a good prognostic value. However, each case has to be assessed individually

High levels of Beta which can suggest a twin pregnancy, cannot be confirmed until the first ultrasound.

The normal values during the first few weeks are:

• 3-4 weeks: 9-130 mIU / ml

• 4-5 weeks: 75-2600 mIU / ml

Can I perform the test early and avoid the wait?

If you perform the test early then the embryo and the hormone levels will be so small that the result will come out negative, whether you are pregnant or not.

Can I perform the test after the recommended date?

Yes, testing a few days later will not influence the outcome of the treatment. In any case, try to do the test as soon as possible due to the fact that waiting to see the result of a treatment is the most difficult moment from an emotional standpoint.

Is the Beta a reliable test?

Yes. A positive result from a reputable laboratory means that embryo implantation has taken place. What is not a positive result is that the pregnancy is progressing normally.

Can I be sure with a positive Beta that the pregnancy will go well?

We cannot assure you of this but the beta test lets us establish a prognosis based on the results. It is a quantitative test that is we find out not only if it is positive or negative, but the exact amount of beta-hCG in the blood. If the value is adequate, the probability of losing before the first scan is very low, so we can establish a good prognosis. On the other hand, if the level is low, the probability that the pregnancy is progressing correctly, decreases.

What is the next step after the Beta if the result is positive?

If the Beta levels in the blood are good then the patients should continue with the medication and schedule an ultrasound scan 2 to 3 weeks later.

What if the result of the Beta is negative?

If the result is negative, meaning that the embryo did not implant, medication should be stopped. The medical team will analyse your case and meet with you to assess the evolution of the treatment cycle and take appropriate measures in order to achieving pregnancy.

What if the beta level is low?

If the level is low, the prognosis is not good, but there is still the possibility of a normal pregnancy. For this reason, it is necessary to continue with the medication and repeat the test a few days later. If after this second test an adequate increase in Beta levels can be seen, an ultrasound scan is then scheduled.

How to take the test or send a sample?

If you do not have easy and fast access to the test, visit our IB BIOTECH services.

Dr Joaquín Llácer, Medical Directo at Instituto Bernabeu, Elche.

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See the equivalent beta test values for each week of pregnancy in the FAQ that we have dedicated to this topic:

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4 responses so far

  • Rod says:

    Hello everyone,

    I’ve got my wife’s beta hcg test done on the 16th day of transfer and it says 84.14 – is it growing well? or should I wait for a week and check again. By when should I expect it to grow double in count.

    Thanks in advance

    • Dear Rod,

      Fist of all, we would like to thank you for the interest shown in our institution.

      The recommendation is to do the BHCG test after 13 days of the egg retrieval. If the embryos were transferred in day 3 of embryonic development, this would be a normal result. We consider a normal level to be at least 30 mIU / ml.

      Our recommendation at Instituto Bernabeu is that with a normal BHCG result, if the clinical history of the patient allows it, it is not necessary to repeat the BHCG test and directly perform ultrasound at 2-3 weeks to confirm pregnancy.

      BHCG results should double every 48 hours from the first one.

      We wish you all the best.

      Best Regards,

      Individualized Guidance Unit

  • Mayo says:

    Friday October17th I had 2 Blastocyst (D5T)
    The blood result
    first HCG on the OCT 28 ( 12DPT) result was 22.55
    second HCG OCT 30 ( 14DPT) result was 79.76
    third HCG NOV 4 (18DPT) result was 83.36
    Fort HCG NOV 6 (20DPT) result was 138.40

    Can this end up in normal pregnancy ?
    Any advice

    • ibernabeu_internacional says:

      Thank you for trusting our institution and sharing your concerns with us. As I’m sure you understand, due to our complete lack of knowledge of your medical history, it would be unwise and unprofessional for us to answer you through this media.
      We encourage you to consult the specialist team that took care of your case. They would be the best people to answer your particular concern. If there is anything else we can do to help, please do not hesitate to contact us directly at:
      Kind regards and best of luck!
      Instituto Bernabeu International Department

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