One out of eight women will contract breast cancer during our lives and a large majority of the cases have a genetic component. Thanks to genetics we can study if you have a predisposition and so can then take preventative measures. IB BIOTECH is a pioneering centre in the study of these linked genes.
Genetics is an essential tool in medicine due to the fact that a considerable percentage of human health issues have a hereditary component. Any genetic-based illness can be diagnosed via techniques in molecular biology
The majority of breast cancers are sporadic cancers, i.e. there is no indication to hereditary susceptibility to developing the illness. But there is a group, estimated at 10%, where a hereditary predisposition to cancer plays its part. A third of hereditary breast cancers are due to mutations in BRCA1, a further third are because of mutations in BRCA2 and the rest are due to other genes. Breast cancers associated with mutations in BRCA1 arise in pre-menopause (average age 42) and the development of contralateral breast cancer within 5 years is approximately 30% in women who are carriers of the mutation in BRCA1. Alterations in the gene BRCA2 are linked to male breast cancer.
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